EC number:4.2.1.75
| ID: | 4.2.1.75 |
|---|---|
| Description: | Uroporphyrinogen-III synthase. |
| Alternative Name: |
Uroporphyrinogen-III cosynthetase. Uroporphyrinogen-III cosynthase. Hydroxymethylbilane hydro-lyase (cyclizing). |
| Cath: | 3.30.160.40; 3.40.190.10; 3.40.50.10090; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.1.75 |
| BRENDA Enzyme Link: | BRENDA 4.2.1.75 |
| KEGG Enzyme Link: | KEGG4.2.1.75 |
| BioCyc Enzyme Link: | BioCyc 4.2.1.75 |
| ExPASy Enzyme Link: | ExPASy4.2.1.75 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.1.75 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.1.75 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.1.75 |
| IntEnz Enzyme Link: | IntEnz 4.2.1.75 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.1.75 |
| RHEA:18965 | hydroxymethylbilane = H2O + uroporphyrinogen III |
| RULE(radius=1) | |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and properties of uroporphyrinogen III synthase from human erythrocytes. | Tsai SF, Bishop DF, Desnick RJ | 1987 Jan 25 | 3805019 |
| Bacterial heme biosynthesis and its biotechnological application. | Frankenberg N, Moser J, Jahn D | 2003 Dec | 13680202 |
| Structural diversity in metal ion chelation and the structure of uroporphyrinogen III synthase. | Schubert HL, Raux E, Matthews MA, Phillips JD, Wilson KS, Hill CP, Warren MJ | 2002 Aug | 12196144 |
| Crystal structure of human uroporphyrinogen III synthase. | Mathews MA, Schubert HL, Whitby FG, Alexander KJ, Schadick K, Bergonia HA, Phillips JD, Hill CP | 2001 Nov 1 | 11689424 |
| Biosynthesis of the pigments of life: formation of the macrocycle. | Battersby AR, Fookes CJ, Matcham GW, McDonald E | 1980 May 1 | 6769048 |