EC number:4.2.1.93
| ID: | 4.2.1.93 |
|---|---|
| Description: | ATP-dependent NAD(P)H-hydrate dehydratase. |
| Alternative Name: |
ATP-dependent H(4)NAD(P)OH dehydratase. |
| Cath: | 3.40.1190.20; 3.40.50.10260; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.1.93 |
| BRENDA Enzyme Link: | BRENDA 4.2.1.93 |
| KEGG Enzyme Link: | KEGG4.2.1.93 |
| BioCyc Enzyme Link: | BioCyc 4.2.1.93 |
| ExPASy Enzyme Link: | ExPASy4.2.1.93 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.1.93 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.1.93 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.1.93 |
| IntEnz Enzyme Link: | IntEnz 4.2.1.93 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.1.93 |
| RHEA:32231 | (6S)-NADPHX + ATP = ADP + H(+) + NADPH + phosphate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH;+0:3](-[*:4])-[OH;+0:5].[*:6]=[P;H0;+0:7](-[*:8])(-[*:9])-[O;H0;+0:10]-[*:11]>>[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[*:11]-[OH;+0:10].[*:6]=[P;H0;+0:7](-[*:8])(-[*:9])-[OH;+0:5] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Equilibrium of 5,6-hydration of NADH and mechanism of ATP-dependent dehydration. | Acheson SA, Kirkman HN, Wolfenden R | 1988 Sep 20 | 3061454 |
| Extremely conserved ATP- or ADP-dependent enzymatic system for nicotinamide nucleotide repair. | Marbaix AY, Noël G, Detroux AM, Vertommen D, Van Schaftingen E, Linster CL | 2011 Dec 2 | 21994945 |
| RHEA:19017 | (6S)-NADHX + ATP = ADP + H(+) + NADH + phosphate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH;+0:3](-[*:4])-[OH;+0:5].[*:6]=[P;H0;+0:7](-[*:8])(-[*:9])-[O;H0;+0:10]-[*:11]>>[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[*:11]-[OH;+0:10].[*:6]=[P;H0;+0:7](-[*:8])(-[*:9])-[OH;+0:5] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Equilibrium of 5,6-hydration of NADH and mechanism of ATP-dependent dehydration. | Acheson SA, Kirkman HN, Wolfenden R | 1988 Sep 20 | 3061454 |
| Extremely conserved ATP- or ADP-dependent enzymatic system for nicotinamide nucleotide repair. | Marbaix AY, Noël G, Detroux AM, Vertommen D, Van Schaftingen E, Linster CL | 2011 Dec 2 | 21994945 |