EC number:4.2.1.99
| ID: | 4.2.1.99 |
|---|---|
| Description: | 2-methylisocitrate dehydratase. |
| Alternative Name: |
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase. |
| Cath: | 3.20.19.10; 3.30.499.10; 3.40.1060.10; 1.25.40.310; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.1.99 |
| BRENDA Enzyme Link: | BRENDA 4.2.1.99 |
| KEGG Enzyme Link: | KEGG4.2.1.99 |
| BioCyc Enzyme Link: | BioCyc 4.2.1.99 |
| ExPASy Enzyme Link: | ExPASy4.2.1.99 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.1.99 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.1.99 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.1.99 |
| IntEnz Enzyme Link: | IntEnz 4.2.1.99 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.1.99 |
| RHEA:17941 | (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[*:3])(-[OH;+0:4])-[CH;+0:5](-[*:6])-[*:7]>>[*:1]-[C;H0;+0:2](-[*:3])=[C;H0;+0:5](-[*:6])-[*:7].[OH2;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Oxidation of propionate to pyruvate in Escherichia coli. Involvement of methylcitrate dehydratase and aconitase. | Brock M, Maerker C, Schütz A, Völker U, Buckel W | 2002 Dec | 12473114 |