EC number:4.2.2.1
| ID: | 4.2.2.1 |
|---|---|
| Description: | Hyaluronate lyase. |
| Alternative Name: |
Spreading factor. Mucinase. Hyaluronidase. |
| Cath: | 1.10.1240.20; 1.10.530.10; 1.25.20.10; 1.50.10.10; 1.50.10.100; 2.60.120.260; 2.60.220.10; 2.60.40.1380; 2.70.98.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.2.1 |
| BRENDA Enzyme Link: | BRENDA 4.2.2.1 |
| KEGG Enzyme Link: | KEGG4.2.2.1 |
| BioCyc Enzyme Link: | BioCyc 4.2.2.1 |
| ExPASy Enzyme Link: | ExPASy4.2.2.1 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.2.1 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.2.1 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.2.1 |
| IntEnz Enzyme Link: | IntEnz 4.2.2.1 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.2.1 |
| RHEA:50240 | [hyaluronan](n) = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine + H2O |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[OH;+0:3])-[CH;+0:4](-[*:5])-[*:6]>>[*:1]-[CH;+0:2]=[C;H0;+0:4](-[*:5])-[*:6].[OH2;+0:3] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Extracellular and intracellular polygllacturonic acid trans-eliminases of Erwinia carotovora. | Moran F, Nasuno S, Starr MP | 1968 Feb | 5642600 |
| Hyaluronidases. | MEYER K, RAPPORT MM | 1952 | 14943668 |
| The formation of unsaturated disacharides from mucopoly-saccharides and their cleavage to alpha-keto acid by bacterial enzymes. | LINKER A, HOFFMAN P, MEYER K, SAMPSON P, KORN ED | 1960 Nov | 13762462 |