Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.107
Description:(+)-car-3-ene synthase.
Alternative Name: 3-carene cyclase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.107
BRENDA Enzyme Link: BRENDA 4.2.3.107
KEGG Enzyme Link: KEGG4.2.3.107
BioCyc Enzyme Link: BioCyc 4.2.3.107
ExPASy Enzyme Link: ExPASy4.2.3.107
EC2PDB Enzyme Link: EC2PDB 4.2.3.107
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.107
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.107
IntEnz Enzyme Link: IntEnz 4.2.3.107
MEDLINE Enzyme Link: MEDLINE 4.2.3.107
MSA:

4.2.3.107;

Phylogenetic Tree:

4.2.3.107;

Uniprot:
M-CSA:
RHEA:32539 (2E)-geranyl diphosphate = (+)-car-3-ene + diphosphate
RULE(radius=1) ([*:1]-[CH2;+0:2]-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[*:6].[*:7]-[CH2;+0:8]-[O;H0;+0:9]-[*:10])>>[*:7]-[CH2;+0:8]-[CH;+0:3]1-[CH;+0:2](-[*:1])-[C;H0;+0:4]-1(-[*:5])-[*:6].[*:10]-[OH;+0:9]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Biosynthesis of monoterpenes: regio- and stereochemistry of (+)-3-carene biosynthesis.Savage TJ, Croteau R1993 Sep8373196
An integrated genomic, proteomic and biochemical analysis of (+)-3-carene biosynthesis in Sitka spruce (Picea sitchensis) genotypes that are resistant or susceptible to white pine weevil.Hall DE, Robert JA, Keeling CI, Domanski D, Quesada AL, Jancsik S, Kuzyk MA, Hamberger B, Borchers CH, Bohlmann J2011 Mar21323772
Targeted isolation, sequence assembly and characterization of two white spruce (Picea glauca) BAC clones for terpenoid synthase and cytochrome P450 genes involved in conifer defence reveal insights into a conifer genome.Hamberger B, Hall D, Yuen M, Oddy C, Hamberger B, Keeling CI, Ritland C, Ritland K, Bohlmann J2009 Aug 619656416
Monoterpene synthases of Pinus contorta and related conifers. A new class of terpenoid cyclase.Savage TJ, Hatch MW, Croteau R1994 Feb 118307957
Monoterpene synthases from gymnosperms and angiosperms: stereospecificity and inactivation by cysteinyl- and arginyl-directed modifying reagents.Savage TJ, Ichii H, Hume SD, Little DB, Croteau R1995 Jul 107625832
Traumatic resin defense in Norway spruce (Picea abies): methyl jasmonate-induced terpene synthase gene expression, and cDNA cloning and functional characterization of (+)-3-carene synthase.Fäldt J, Martin D, Miller B, Rawat S, Bohlmann J2003 Jan12602896