EC number:4.2.3.108
| ID: | 4.2.3.108 |
|---|---|
| Description: | 1,8-cineole synthase. |
| Alternative Name: |
1,8-cineole cyclase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.3.108 |
| BRENDA Enzyme Link: | BRENDA 4.2.3.108 |
| KEGG Enzyme Link: | KEGG4.2.3.108 |
| BioCyc Enzyme Link: | BioCyc 4.2.3.108 |
| ExPASy Enzyme Link: | ExPASy4.2.3.108 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.3.108 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.3.108 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.3.108 |
| IntEnz Enzyme Link: | IntEnz 4.2.3.108 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.3.108 |
EC number:4.2.3.108
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:32543 | (2E)-geranyl diphosphate + H2O = 1,8-cineole + diphosphate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[*:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[*:8])=[CH;+0:9]-[CH2;+0:10]-[O;H0;+0:11]-[*:12].[OH2;+0:13]>>[*:1]-[C;H0;+0:2]12-[*:3]-[*:4]-[CH;+0:5](-[CH2;+0:10]-[CH2;+0:9]-1)-[C;H0;+0:6](-[*:7])(-[*:8])-[O;H0;+0:13]-2.[*:12]-[OH;+0:11] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Monoterpene synthases from common sage (Salvia officinalis). cDNA isolation, characterization, and functional expression of (+)-sabinene synthase, 1,8-cineole synthase, and (+)-bornyl diphosphate synthase. | Wise ML, Savage TJ, Katahira E, Croteau R | 1998 Jun 12 | 9614092 |
| Characterization of a root-specific Arabidopsis terpene synthase responsible for the formation of the volatile monoterpene 1,8-cineole. | Chen F, Ro DK, Petri J, Gershenzon J, Bohlmann J, Pichersky E, Tholl D | 2004 Aug | 15299125 |
| Biosynthesis of monoterpenes: partial purification, characterization, and mechanism of action of 1,8-cineole synthase. | Croteau R, Alonso WR, Koepp AE, Johnson MA | 1994 Feb 15 | 8117108 |
| Functional and evolutionary relationships between terpene synthases from Australian Myrtaceae. | Keszei A, Brubaker CL, Carter R, Köllner T, Degenhardt J, Foley WJ | 2010 Jun | 20399476 |
| Alternative termination chemistries utilized by monoterpene cyclases: chimeric analysis of bornyl diphosphate, 1,8-cineole, and sabinene synthases. | Peters RJ, Croteau RB | 2003 Sep 15 | 12941302 |