Enzyme

Download
EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.116
Description:(+)-camphene synthase.
Cath: 1.10.600.10; 1.50.10.130;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.116
BRENDA Enzyme Link: BRENDA 4.2.3.116
KEGG Enzyme Link: KEGG4.2.3.116
BioCyc Enzyme Link: BioCyc 4.2.3.116
ExPASy Enzyme Link: ExPASy4.2.3.116
EC2PDB Enzyme Link: EC2PDB 4.2.3.116
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.116
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.116
IntEnz Enzyme Link: IntEnz 4.2.3.116
MEDLINE Enzyme Link: MEDLINE 4.2.3.116
MSA:

4.2.3.116;

Phylogenetic Tree:

4.2.3.116;

Uniprot:
M-CSA:
RHEA:32567 (2E)-geranyl diphosphate = (1R,4S)-camphene + diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])=[CH;+0:4]-[*:5]-[*:6]-[C;H0;+0:7](-[CH3;+0:8])=[CH;+0:9]-[CH2;+0:10]-[O;H0;+0:11]-[*:12]>>[*:1]-[C;H0;+0:2]1(-[*:3])-[C;H0;+0:9](=[CH2;+0:10])-[CH;+0:7]2-[*:6]-[*:5]-[CH;+0:4]-1-[CH2;+0:8]-2.[*:12]-[OH;+0:11]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Monoterpene synthases from common sage (Salvia officinalis). cDNA isolation, characterization, and functional expression of (+)-sabinene synthase, 1,8-cineole synthase, and (+)-bornyl diphosphate synthase.Wise ML, Savage TJ, Katahira E, Croteau R1998 Jun 129614092
Monoterpene biosynthesis: isotope effects associated with bicyclic olefin formation catalyzed by pinene synthases from sage (Salvia officinalis).Wagschal KC, Pyun HJ, Coates RM, Croteau R1994 Feb 18109978
Pinene cyclases I and II. Two enzymes from sage (Salvia officinalis) which catalyze stereospecific cyclizations of geranyl pyrophosphate to monoterpene olefins of opposite configuration.Gambliel H, Croteau R1984 Jan 256693393
Biosynthesis of monoterpenes. Enantioselectivity in the enzymatic cyclization of (+)- and (-)-linalyl pyrophosphate to (+)- and (-)-pinene and (+)- and (-)-camphene.Croteau R, Satterwhite DM, Cane DE, Chang CC1988 Jul 253392006