EC number:4.2.3.118

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.118
Description:2-methylisoborneol synthase.
Alternative Name: MIB synthase.
2-MIB cyclase.
Cath: 1.10.600.10; 3.40.50.150;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.118
BRENDA Enzyme Link: BRENDA 4.2.3.118
KEGG Enzyme Link: KEGG4.2.3.118
BioCyc Enzyme Link: BioCyc 4.2.3.118
ExPASy Enzyme Link: ExPASy4.2.3.118
EC2PDB Enzyme Link: EC2PDB 4.2.3.118
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.118
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.118
IntEnz Enzyme Link: IntEnz 4.2.3.118
MEDLINE Enzyme Link: MEDLINE 4.2.3.118

EC number:4.2.3.118

MSA:

4.2.3.118;
Phylogenetic Tree:

4.2.3.118;
Uniprot:
M-CSA:
RHEA:32571 (E)-2-methylgeranyl diphosphate + H2O = 2-methylisoborneol + diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[*:8])=[C;H0;+0:9](-[*:10])-[CH2;+0:11]-[O;H0;+0:12]-[*:13].[OH2;+0:14]>>[*:1]-[C;H0;+0:2]12-[*:3]-[*:4]-[CH;+0:5](-[CH2;+0:11]-[C;H0;+0:9]-1(-[*:10])-[OH;+0:14])-[C;H0;+0:6]-2(-[*:7])-[*:8].[*:13]-[OH;+0:12]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Biosynthesis of 2-methylisoborneol in cyanobacteria.Giglio S, Chou WK, Ikeda H, Cane DE, Monis PT2011 Feb 121174459
Biochemistry and molecular genetics of the biosynthesis of the earthy odorant methylisoborneol in Streptomyces coelicolor.Wang CM, Cane DE2008 Jul 1618563898
Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol.Komatsu M, Tsuda M, Omura S, Oikawa H, Ikeda H2008 May 2718492804