Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.119
Description:(-)-alpha-pinene synthase.
Alternative Name: (-)-alpha-pinene/(-)-camphene synthase.
(-)-alpha-pinene cyclase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.119
BRENDA Enzyme Link: BRENDA 4.2.3.119
KEGG Enzyme Link: KEGG4.2.3.119
BioCyc Enzyme Link: BioCyc 4.2.3.119
ExPASy Enzyme Link: ExPASy4.2.3.119
EC2PDB Enzyme Link: EC2PDB 4.2.3.119
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.119
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.119
IntEnz Enzyme Link: IntEnz 4.2.3.119
MEDLINE Enzyme Link: MEDLINE 4.2.3.119
MSA:

4.2.3.119;

Phylogenetic Tree:

4.2.3.119;

Uniprot:
M-CSA:
RHEA:25488 (2E)-geranyl diphosphate = (1S,5S)-alpha-pinene + diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])=[CH;+0:4]-[*:5]-[CH2;+0:6]-[*:7]=[*:8]-[CH2;+0:9]-[O;H0;+0:10]-[*:11]>>[*:1]-[C;H0;+0:2]1(-[*:3])-[CH;+0:6]2-[*:7]=[*:8]-[CH2;+0:9]-[CH;+0:4]-1-[*:5]-2.[*:11]-[OH;+0:10]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Monoterpene synthases from grand fir (Abies grandis). cDNA isolation, characterization, and functional expression of myrcene synthase, (-)-(4S)-limonene synthase, and (-)-(1S,5S)-pinene synthase.Bohlmann J, Steele CL, Croteau R1997 Aug 299268308
cDNA cloning, characterization, and functional expression of four new monoterpene synthase members of the Tpsd gene family from grand fir (Abies grandis).Bohlmann J, Phillips M, Ramachandiran V, Katoh S, Croteau R1999 Aug 1510441373
Mutational analysis of a monoterpene synthase reaction: altered catalysis through directed mutagenesis of (-)-pinene synthase from Abies grandis.Hyatt DC, Croteau R2005 Jul 1515978541
Characterization of four terpene synthase cDNAs from methyl jasmonate-induced Douglas-fir, Pseudotsuga menziesii.Huber DP, Philippe RN, Godard KA, Sturrock RN, Bohlmann J2005 Jun15921711
Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species.Aharoni A, Giri AP, Verstappen FW, Bertea CM, Sevenier R, Sun Z, Jongsma MA, Schwab W, Bouwmeester HJ2004 Nov15522848
Insect attack and wounding induce traumatic resin duct development and gene expression of (-)-pinene synthase in Sitka spruce.McKay SA, Hunter WL, Godard KA, Wang SX, Martin DM, Bohlmann J, Plant AL2003 Sep12970502
cDNA isolation, functional expression, and characterization of (+)-alpha-pinene synthase and (-)-alpha-pinene synthase from loblolly pine (Pinus taeda): stereocontrol in pinene biosynthesis.Phillips MA, Wildung MR, Williams DC, Hyatt DC, Croteau R2003 Mar 1512623076