EC number:4.2.3.129

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.129
Description:(+)-sativene synthase.
Alternative Name: Cop4.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.129
BRENDA Enzyme Link: BRENDA 4.2.3.129
KEGG Enzyme Link: KEGG4.2.3.129
BioCyc Enzyme Link: BioCyc 4.2.3.129
ExPASy Enzyme Link: ExPASy4.2.3.129
EC2PDB Enzyme Link: EC2PDB 4.2.3.129
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.129
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.129
IntEnz Enzyme Link: IntEnz 4.2.3.129
MEDLINE Enzyme Link: MEDLINE 4.2.3.129

EC number:4.2.3.129

MSA:

4.2.3.129;
Phylogenetic Tree:

4.2.3.129;
Uniprot:
M-CSA:
RHEA:33119 (2E,6E)-farnesyl diphosphate = (+)-sativene + diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[*:8])=[CH;+0:9]-[*:10]-[*:11]-[C;H0;+0:12](-[CH3;+0:13])=[CH;+0:14]-[CH2;+0:15]-[O;H0;+0:16]-[*:17]>>[*:1]-[C;H0;+0:2]12-[*:3]-[*:4]-[CH;+0:5](-[CH;+0:6](-[*:7])-[*:8])-[CH;+0:13]3-[CH;+0:12](-[*:11]-[*:10]-[CH;+0:9]-3-1)-[C;H0;+0:14]-2=[CH2;+0:15].[*:17]-[OH;+0:16]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Selectivity of fungal sesquiterpene synthases: role of the active site's H-1 alpha loop in catalysis.López-Gallego F, Wawrzyn GT, Schmidt-Dannert C2010 Dec20889795
Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isomers.Lopez-Gallego F, Agger SA, Abate-Pella D, Distefano MD, Schmidt-Dannert C2010 May 1720419721
Diversity of sesquiterpene synthases in the basidiomycete Coprinus cinereus.Agger S, Lopez-Gallego F, Schmidt-Dannert C2009 Jun19400802