Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.13
Description:(+)-delta-cadinene synthase.
Alternative Name: D-cadinene synthase.
Cath: 1.10.600.10; 1.50.10.130;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.13
BRENDA Enzyme Link: BRENDA 4.2.3.13
KEGG Enzyme Link: KEGG4.2.3.13
BioCyc Enzyme Link: BioCyc 4.2.3.13
ExPASy Enzyme Link: ExPASy4.2.3.13
EC2PDB Enzyme Link: EC2PDB 4.2.3.13
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.13
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.13
IntEnz Enzyme Link: IntEnz 4.2.3.13
MEDLINE Enzyme Link: MEDLINE 4.2.3.13
MSA:

4.2.3.13;

Phylogenetic Tree:

4.2.3.13;

Uniprot:
M-CSA:
RHEA:19525 (2E,6E)-farnesyl diphosphate = (1S,8aR)-delta-cadinene + diphosphate
RULE(radius=1) ([*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[*:5]-[CH;+0:6]=[*:7].[*:8]-[CH;+0:9]=[C;H0;+0:10](-[*:11])-[*:12])>>[*:1]-[CH;+0:2](-[C;H0;+0:6](-[*:5])=[*:7])-[CH;+0:9](-[*:8])-[CH;+0:10](-[*:11])-[*:12].[*:4]-[OH;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Sesquiterpene synthases from grand fir (Abies grandis). Comparison of constitutive and wound-induced activities, and cDNA isolation, characterization, and bacterial expression of delta-selinene synthase and gamma-humulene synthase.Steele CL, Crock J, Bohlmann J, Croteau R1998 Jan 239442047
Purification of (+)-delta-cadinene synthase, a sesquiterpene cyclase from bacteria-inoculated cotton foliar tissue.Davis EM, Tsuji J, Davis GD, Pierce ML, Essenberg M1996 Mar8728715
Cloning, expression, and characterization of (+)-delta-cadinene synthase: a catalyst for cotton phytoalexin biosynthesis.Chen XY, Chen Y, Heinstein P, Davisson VJ1995 Dec 208554317
Crystal structure of (+)-delta-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis.Gennadios HA, Gonzalez V, Di Costanzo L, Li A, Yu F, Miller DJ, Allemann RK, Christianson DW2009 Jul 719489610
The molecular and biochemical basis for varietal variation in sesquiterpene content in melon (Cucumis melo L.) rinds.Portnoy V, Benyamini Y, Bar E, Harel-Beja R, Gepstein S, Giovannoni JJ, Schaffer AA, Burger J, Tadmor Y, Lewinsohn E, Katzir N2008 Apr18264780