EC number:4.2.3.134

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.134
Description:5-phosphonooxy-L-lysine phospho-lyase.
Alternative Name: 5-phosphohydroxy-L-lysine ammoniophospholyase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.134
BRENDA Enzyme Link: BRENDA 4.2.3.134
KEGG Enzyme Link: KEGG4.2.3.134
BioCyc Enzyme Link: BioCyc 4.2.3.134
ExPASy Enzyme Link: ExPASy4.2.3.134
EC2PDB Enzyme Link: EC2PDB 4.2.3.134
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.134
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.134
IntEnz Enzyme Link: IntEnz 4.2.3.134
MEDLINE Enzyme Link: MEDLINE 4.2.3.134

EC number:4.2.3.134

MSA:

4.2.3.134;
Phylogenetic Tree:

4.2.3.134;
Uniprot:
M-CSA:
RHEA:34091 (5R)-5-phosphooxy-L-lysine + H2O = (S)-2-amino-6-oxohexanoate + NH4(+) + phosphate
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[CH2;+0:5]-[NH2;+0:6].[OH2;+0:7]>>[*:4]-[CH2;+0:3]-[CH;+0:5]=[O;H0;+0:7].[*:1]-[OH;+0:2].[NH3;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Molecular identification of hydroxylysine kinase and of ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolamine.Veiga-da-Cunha M, Hadi F, Balligand T, Stroobant V, Van Schaftingen E2012 Mar 222241472
Degradation of O-phosphohydroxylysine by rat liver. Purification of the phospho-lyase.Tsai CH, Henderson LM1974 Sep 254412716