EC number:4.2.3.136

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.136
Description:Alpha-isocomene synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.136
BRENDA Enzyme Link: BRENDA 4.2.3.136
KEGG Enzyme Link: KEGG4.2.3.136
BioCyc Enzyme Link: BioCyc 4.2.3.136
ExPASy Enzyme Link: ExPASy4.2.3.136
EC2PDB Enzyme Link: EC2PDB 4.2.3.136
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.136
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.136
IntEnz Enzyme Link: IntEnz 4.2.3.136
MEDLINE Enzyme Link: MEDLINE 4.2.3.136

EC number:4.2.3.136

MSA:

4.2.3.136;
Phylogenetic Tree:

4.2.3.136;
Uniprot:
M-CSA:
RHEA:34699 (2E,6E)-farnesyl diphosphate = (-)-alpha-isocomene + diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[CH3;+0:7])-[*:8]-[*:9]-[CH;+0:10]=[C;H0;+0:11](-[*:12])-[CH3;+0:13])=[CH;+0:14]-[CH2;+0:15]-[O;H0;+0:16]-[*:17]>>[*:1]-[C;H0;+0:2]12-[*:3]-[*:4]-[CH;+0:5](-[CH3;+0:7])-[C;H0;+0:6]-13-[*:8]-[*:9]-[CH2;+0:10]-[C;H0;+0:11]-3(-[*:12])-[CH;+0:13]=[C;H0;+0:14]-2-[CH3;+0:15].[*:17]-[OH;+0:16]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The organ-specific expression of terpene synthase genes contributes to the terpene hydrocarbon composition of chamomile essential oils.Irmisch S, Krause ST, Kunert G, Gershenzon J, Degenhardt J, Köllner TG2012 Jun 822682202
Theoretical and experimental analysis of the reaction mechanism of MrTPS2, a triquinane-forming sesquiterpene synthase from chamomile.Hong YJ, Irmisch S, Wang SC, Garms S, Gershenzon J, Zu L, Köllner TG, Tantillo DJ2013 Sep 2723963956