EC number:4.2.3.139

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.139
Description:Valerena-4,7(11)-diene synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.139
BRENDA Enzyme Link: BRENDA 4.2.3.139
KEGG Enzyme Link: KEGG4.2.3.139
BioCyc Enzyme Link: BioCyc 4.2.3.139
ExPASy Enzyme Link: ExPASy4.2.3.139
EC2PDB Enzyme Link: EC2PDB 4.2.3.139
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.139
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.139
IntEnz Enzyme Link: IntEnz 4.2.3.139
MEDLINE Enzyme Link: MEDLINE 4.2.3.139

EC number:4.2.3.139

MSA:

4.2.3.139;
Phylogenetic Tree:

4.2.3.139;
Uniprot:
M-CSA:
RHEA:34467 (2E,6E)-farnesyl diphosphate = diphosphate + valerena-4,7(11)-diene
RULE(radius=1) [*:1]-[C;H0;+0:2](-[CH2;+0:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[CH2;+0:8]-[CH2;+0:9]-[*:10])=[CH;+0:11]-[CH2;+0:12]-[O;H0;+0:13]-[*:14]>>[*:1]-[CH;+0:2]1-[CH2;+0:11]-[CH2;+0:12]-[CH;+0:9](-[*:10])-[C;H0;+0:8]2=[C;H0;+0:6](-[*:7])-[CH2;+0:5]-[*:4]-[CH;+0:3]-2-1.[*:14]-[OH;+0:13]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Functional identification of valerena-1,10-diene synthase, a terpene synthase catalyzing a unique chemical cascade in the biosynthesis of biologically active sesquiterpenes in Valeriana officinalis.Yeo YS, Nybo SE, Chittiboyina AG, Weerasooriya AD, Wang YH, Góngora-Castillo E, Vaillancourt B, Buell CR, DellaPenna D, Celiz MD, Jones AD, Wurtele ES, Ransom N, Dudareva N, Shaaban KA, Tibrewal N, Chandra S, Smillie T, Khan IA, Coates RM, Watt DS, Chappell J2013 Feb 123243312
Enzymatic synthesis of valerena-4,7(11)-diene by a unique sesquiterpene synthase from the valerian plant (Valeriana officinalis).Pyle BW, Tran HT, Pickel B, Haslam TM, Gao Z, MacNevin G, Vederas JC, Kim SU, Ro DK2012 Sep22776156