EC number:4.2.3.145

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.145
Description:Ophiobolin F synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.145
BRENDA Enzyme Link: BRENDA 4.2.3.145
KEGG Enzyme Link: KEGG4.2.3.145
BioCyc Enzyme Link: BioCyc 4.2.3.145
ExPASy Enzyme Link: ExPASy4.2.3.145
EC2PDB Enzyme Link: EC2PDB 4.2.3.145
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.145
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.145
IntEnz Enzyme Link: IntEnz 4.2.3.145
MEDLINE Enzyme Link: MEDLINE 4.2.3.145

EC number:4.2.3.145

MSA:

4.2.3.145;
Phylogenetic Tree:

4.2.3.145;
Uniprot:
M-CSA:
RHEA:41552 (2E,6E,10E,14E)-geranylfarnesyl diphosphate + H2O = diphosphate + ophiobolin F
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[CH2;+0:8]-[*:9]-[CH;+0:10]=[C;H0;+0:11](-[*:12])-[*:13]-[*:14]-[CH;+0:15]=[C;H0;+0:16](-[*:17])-[*:18])=[CH;+0:19]-[CH2;+0:20]-[O;H0;+0:21]-[*:22].[OH2;+0:23]>>[*:1]-[C;H0;+0:2]1(-[OH;+0:23])-[*:3]-[*:4]-[CH;+0:5]2-[C;H0;+0:6](-[*:7])=[CH;+0:8]-[*:9]-[CH;+0:10]3-[CH;+0:15](-[CH;+0:16](-[*:17])-[*:18])-[*:14]-[*:13]-[C;H0;+0:11]-3(-[*:12])-[CH2;+0:20]-[CH;+0:19]-2-1.[*:22]-[OH;+0:21]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Identification of ophiobolin F synthase by a genome mining approach: a sesterterpene synthase from Aspergillus clavatus.Chiba R, Minami A, Gomi K, Oikawa H2013 Feb 123324037