EnzyMine

Download

EC Tree

4. Lyases

4.2 Carbon-oxygen lyases

4.2.3 Acting on phosphates

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

PDB	Click once to unfold,double click to fold.

UniProtKB Enzyme Link:	UniProtKB 4.2.3.146
BRENDA Enzyme Link:	BRENDA 4.2.3.146
KEGG Enzyme Link:	KEGG4.2.3.146
BioCyc Enzyme Link:	BioCyc 4.2.3.146
ExPASy Enzyme Link:	ExPASy4.2.3.146
EC2PDB Enzyme Link:	EC2PDB 4.2.3.146
ExplorEnz Enzyme Link:	ExplorEnz 4.2.3.146
PRIAM enzyme-specific profiles Link:	PRIAM 4.2.3.146
IntEnz Enzyme Link:	IntEnz 4.2.3.146
MEDLINE Enzyme Link:	MEDLINE 4.2.3.146

RHEA:41628	geranylgeranyl diphosphate + H2O = cyclooctat-9-en-7-ol + diphosphate
RULE(radius=1)	[:1]-[C;H0;+0:2](-[:3]-[:4]-[CH;+0:5]=[C;H0;+0:6](-[:7])-[:8]-[CH2;+0:9]-[CH;+0:10]=[C;H0;+0:11](-[:12])-[:13]-[:14]-[CH;+0:15]=[C;H0;+0:16](-[:17])-[:18])=[CH;+0:19]-[CH2;+0:20]-[O;H0;+0:21]-[:22].[OH2;+0:23]>>[:1]-[CH;+0:2]1-[:3]-[:4]-[CH;+0:5]2-[CH;+0:19]-1-[CH2;+0:20]-[C;H0;+0:11]1(-[:12])-[:13]-[:14]-[CH;+0:15](-[CH;+0:16](-[:17])-[:18])-[C;H0;+0:10]-1=[CH;+0:9]-[:8]-[C;H0;+0:6]-2(-[:7])-[OH;+0:23].[:22]-[OH;+0:21]
Reaction
Core-to-Core	No scaffolds atoms were exchanged as a result of the reaction

Title	Authors	Date	PubMed ID
Cloning and heterologous expression of the cyclooctatin biosynthetic gene cluster afford a diterpene cyclase and two p450 hydroxylases.	Kim SY, Zhao P, Igarashi M, Sawa R, Tomita T, Nishiyama M, Kuzuyama T	2009 Jul 31	19635410