EC number:4.2.3.153

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.153
Description:(5-formylfuran-3-yl)methyl phosphate synthase.
Alternative Name: 4-HFC-P synthase.
2-furaldehyde phosphate synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.153
BRENDA Enzyme Link: BRENDA 4.2.3.153
KEGG Enzyme Link: KEGG4.2.3.153
BioCyc Enzyme Link: BioCyc 4.2.3.153
ExPASy Enzyme Link: ExPASy4.2.3.153
EC2PDB Enzyme Link: EC2PDB 4.2.3.153
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.153
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.153
IntEnz Enzyme Link: IntEnz 4.2.3.153
MEDLINE Enzyme Link: MEDLINE 4.2.3.153

EC number:4.2.3.153

MSA:

4.2.3.153;
Phylogenetic Tree:

4.2.3.153;
Uniprot:
M-CSA:
RHEA:43536 2 D-glyceraldehyde 3-phosphate = 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + 2 H2O + phosphate
RULE(radius=1) [*:1]-[CH;+0:2](-[OH;+0:3])-[CH2;+0:4]-[O;H0;+0:5]-[*:6].[*:7]-[CH;+0:8](-[OH;+0:9])-[CH;+0:10]=[O;H0;+0:11]>>[*:6]-[OH;+0:5].[*:7]-[c;H0;+0:8]1:[cH;+0:10]:[o;H0;+0:3]:[c;H0;+0:2](-[*:1]):[cH;+0:4]:1.[OH2;+0:9].[OH2;+0:11]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Mechanism of the Enzymatic Synthesis of 4-(Hydroxymethyl)-2- furancarboxaldehyde-phosphate (4-HFC-P) from Glyceraldehyde-3-phosphate Catalyzed by 4-HFC-P Synthase.Wang Y, Jones MK, Xu H, Ray WK, White RH2015 May 1925905665
Structure of the methanofuran/methanopterin-biosynthetic enzyme MJ1099 from Methanocaldococcus jannaschii.Bobik TA, Morales EJ, Shin A, Cascio D, Sawaya MR, Arbing M, Yeates TO, Rasche ME2014 Nov25372812
Identification and characterization of a tyramine-glutamate ligase (MfnD) involved in methanofuran biosynthesis.Wang Y, Xu H, Harich KC, White RH2014 Oct 725211225
Biosynthesis of the 5-(Aminomethyl)-3-furanmethanol moiety of methanofuran.Miller D, Wang Y, Xu H, Harich K, White RH2014 Jul 2224977328