EC number:4.2.3.157

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.157
Description:(+)-isoafricanol synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.157
BRENDA Enzyme Link: BRENDA 4.2.3.157
KEGG Enzyme Link: KEGG4.2.3.157
BioCyc Enzyme Link: BioCyc 4.2.3.157
ExPASy Enzyme Link: ExPASy4.2.3.157
EC2PDB Enzyme Link: EC2PDB 4.2.3.157
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.157
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.157
IntEnz Enzyme Link: IntEnz 4.2.3.157
MEDLINE Enzyme Link: MEDLINE 4.2.3.157

EC number:4.2.3.157

MSA:

4.2.3.157;
Phylogenetic Tree:

4.2.3.157;
Uniprot:
M-CSA:
RHEA:53616 (2E,6E)-farnesyl diphosphate + H2O = (+)-isoafricanol + diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[*:8]-[CH2;+0:9]-[CH;+0:10]=[C;H0;+0:11](-[*:12])-[*:13])=[CH;+0:14]-[CH2;+0:15]-[O;H0;+0:16]-[*:17].[OH2;+0:18]>>[*:1]-[CH;+0:2]1-[*:3]-[*:4]-[CH;+0:5]2-[C;H0;+0:14]-1(-[OH;+0:18])-[CH2;+0:15]-[C;H0;+0:11](-[*:12])(-[*:13])-[CH2;+0:10]-[CH;+0:9]1-[*:8]-[C;H0;+0:6]-2-1-[*:7].[*:17]-[OH;+0:16]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Isoafricanol synthase from Streptomyces malaysiensis.Rabe P, Samborskyy M, Leadlay PF, Dickschat JS2017 Mar 2128247907
Identification of isoafricanol and its terpene cyclase in Streptomyces violaceusniger using CLSA-NMR.Riclea R, Citron CA, Rinkel J, Dickschat JS2014 Apr 2524626486