Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.158
Description:(-)-spiroviolene synthase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.158
BRENDA Enzyme Link: BRENDA 4.2.3.158
KEGG Enzyme Link: KEGG4.2.3.158
BioCyc Enzyme Link: BioCyc 4.2.3.158
ExPASy Enzyme Link: ExPASy4.2.3.158
EC2PDB Enzyme Link: EC2PDB 4.2.3.158
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.158
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.158
IntEnz Enzyme Link: IntEnz 4.2.3.158
MEDLINE Enzyme Link: MEDLINE 4.2.3.158
MSA:

4.2.3.158;

Phylogenetic Tree:

4.2.3.158;

Uniprot:
M-CSA:
RHEA:53620 all-trans-geranylgeranyl diphosphate = (-)-spiroviolene + diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[CH2;+0:3]-[CH2;+0:4]-[*:5]=[C;H0;+0:6](-[CH3;+0:7])-[CH2;+0:8]-[*:9]-[CH;+0:10]=[C;H0;+0:11](-[CH3;+0:12])-[CH2;+0:13]-[*:14]-[CH;+0:15]=[C;H0;+0:16](-[*:17])-[CH3;+0:18])=[CH;+0:19]-[CH2;+0:20]-[O;H0;+0:21]-[*:22]>>[*:1]-[C;H0;+0:2]1(-[CH3;+0:18])-[CH2;+0:19]-[CH2;+0:20]-[C;H0;+0:4]2(-[CH3;+0:12])-[*:5]=[C;H0;+0:6]3-[CH;+0:8](-[*:9]-[CH2;+0:10]-[C;H0;+0:11]-34-[CH;+0:13](-[CH3;+0:7])-[*:14]-[CH2;+0:15]-[CH;+0:16]-4-[*:17])-[CH;+0:3]-1-2.[*:22]-[OH;+0:21]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Mechanistic Investigations of Two Bacterial Diterpene Cyclases: Spiroviolene Synthase and Tsukubadiene Synthase.Rabe P, Rinkel J, Dolja E, Schmitz T, Nubbemeyer B, Luu TH, Dickschat JS2017 Mar 128146322