EC number:4.2.3.162

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.162
Description:(-)-alpha-amorphene synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.162
BRENDA Enzyme Link: BRENDA 4.2.3.162
KEGG Enzyme Link: KEGG4.2.3.162
BioCyc Enzyme Link: BioCyc 4.2.3.162
ExPASy Enzyme Link: ExPASy4.2.3.162
EC2PDB Enzyme Link: EC2PDB 4.2.3.162
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.162
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.162
IntEnz Enzyme Link: IntEnz 4.2.3.162
MEDLINE Enzyme Link: MEDLINE 4.2.3.162

EC number:4.2.3.162

MSA:

4.2.3.162;
Phylogenetic Tree:

4.2.3.162;
Uniprot:
M-CSA:
RHEA:53640 (2E,6E)-farnesyl diphosphate = (-)-alpha-amorphene + diphosphate
RULE(radius=1) ([*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[*:5]-[CH;+0:6]=[C;H0;+0:7](-[*:8])-[CH2;+0:9]-[*:10]-[CH;+0:11]=[C;H0;+0:12](-[*:13])-[*:14])>>[*:1]-[CH;+0:2]1-[CH;+0:6](-[*:5])-[C;H0;+0:7](-[*:8])=[CH;+0:9]-[*:10]-[CH;+0:11]-1-[CH;+0:12](-[*:13])-[*:14].[*:4]-[OH;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Mechanistic investigations on six bacterial terpene cyclases.Rabe P, Schmitz T, Dickschat JS201627829890
Lessons from 1,3-Hydride Shifts in Sesquiterpene Cyclizations.Rinkel J, Rabe P, Garbeva P, Dickschat JS2016 Oct 1727666571
Rapid chemical characterization of bacterial terpene synthases.Rabe P, Dickschat JS2013 Feb 423307484