EC number:4.2.3.164

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.164
Description:(+)-eremophilene synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.164
BRENDA Enzyme Link: BRENDA 4.2.3.164
KEGG Enzyme Link: KEGG4.2.3.164
BioCyc Enzyme Link: BioCyc 4.2.3.164
ExPASy Enzyme Link: ExPASy4.2.3.164
EC2PDB Enzyme Link: EC2PDB 4.2.3.164
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.164
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.164
IntEnz Enzyme Link: IntEnz 4.2.3.164
MEDLINE Enzyme Link: MEDLINE 4.2.3.164

EC number:4.2.3.164

MSA:

4.2.3.164;
Phylogenetic Tree:

4.2.3.164;
Uniprot:
M-CSA:
RHEA:52804 (2E,6E)-farnesyl diphosphate = (+)-eremophilene + diphosphate
RULE(radius=1) ([*:1]-[C;H0;+0:2](-[*:3])=[CH;+0:4]-[CH2;+0:5]-[O;H0;+0:6]-[*:7].[*:8]=[C;H0;+0:9](-[CH3;+0:10])-[*:11]-[*:12]-[CH;+0:13]=[C;H0;+0:14](-[*:15])-[CH3;+0:16])>>[*:1]-[CH;+0:2](-[*:3])-[C;H0;+0:4]1(-[CH3;+0:10])-[CH2;+0:5]-[CH;+0:13](-[C;H0;+0:14](-[*:15])=[CH2;+0:16])-[*:12]-[*:11]-[C;H0;+0:9]-1=[*:8].[*:7]-[OH;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Mechanistic Characterisation of Two Sesquiterpene Cyclases from the Plant Pathogenic Fungus Fusarium fujikuroi.Burkhardt I, Siemon T, Henrot M, Studt L, Rösler S, Tudzynski B, Christmann M, Dickschat JS2016 Jul 1827294564
Characterization of the gene cluster CYP264B1-geoA from Sorangium cellulosum So ce56: biosynthesis of (+)-eremophilene and its hydroxylation.Schifrin A, Ly TT, Günnewich N, Zapp J, Thiel V, Schulz S, Hannemann F, Khatri Y, Bernhardt R2015 Jan 1925504914