EC number:4.2.3.166

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.166
Description:(+)-(1(10)E,4E,6S,7R)-germacradien-6-ol synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.166
BRENDA Enzyme Link: BRENDA 4.2.3.166
KEGG Enzyme Link: KEGG4.2.3.166
BioCyc Enzyme Link: BioCyc 4.2.3.166
ExPASy Enzyme Link: ExPASy4.2.3.166
EC2PDB Enzyme Link: EC2PDB 4.2.3.166
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.166
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.166
IntEnz Enzyme Link: IntEnz 4.2.3.166
MEDLINE Enzyme Link: MEDLINE 4.2.3.166

EC number:4.2.3.166

MSA:

4.2.3.166;
Phylogenetic Tree:

4.2.3.166;
Uniprot:
M-CSA:
RHEA:12192 (2E,6E)-farnesyl diphosphate + H2O = (+)-(1(10)E,4E,6S,7R)-germacradien-6-ol + diphosphate
RULE(radius=1) ([*:1]-[CH2;+0:2]-[O;H0;+0:3]-[P;H0;+0:4](-[*:5])(=[*:6])-[*:7].[*:8]-[CH;+0:9]=[C;H0;+0:10](-[*:11])-[*:12]).[OH2;+0:13]>>[*:1]-[CH;+0:2](-[OH;+0:3])-[CH;+0:9](-[*:8])-[CH;+0:10](-[*:11])-[*:12].[*:5]-[P;H0;+0:4](=[*:6])(-[*:7])-[OH;+0:13]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Conformational Analysis, Thermal Rearrangement, and EI-MS Fragmentation Mechanism of (1(10)E,4E,6S,7R)-Germacradien-6-ol by (13)C-Labeling Experiments.Rabe P, Barra L, Rinkel J, Riclea R, Citron CA, Klapschinski TA, Janusko A, Dickschat JS2015 Nov 226361082