EC number:4.2.3.171

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.171
Description:(+)-corvol ether A synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.171
BRENDA Enzyme Link: BRENDA 4.2.3.171
KEGG Enzyme Link: KEGG4.2.3.171
BioCyc Enzyme Link: BioCyc 4.2.3.171
ExPASy Enzyme Link: ExPASy4.2.3.171
EC2PDB Enzyme Link: EC2PDB 4.2.3.171
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.171
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.171
IntEnz Enzyme Link: IntEnz 4.2.3.171
MEDLINE Enzyme Link: MEDLINE 4.2.3.171

EC number:4.2.3.171

MSA:

4.2.3.171;
Phylogenetic Tree:

4.2.3.171;
Uniprot:
M-CSA:
RHEA:53648 (2E,6E)-farnesyl diphosphate + H2O = (+)-corvol ether A + diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3]-[CH2;+0:4]-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[*:8]-[*:9]-[CH;+0:10]=[C;H0;+0:11](-[*:12])-[*:13])=[CH;+0:14]-[CH2;+0:15]-[O;H0;+0:16]-[*:17].[OH2;+0:18]>>[*:1]-[C;H0;+0:2]12-[*:3]-[CH;+0:4]3-[CH;+0:5](-[CH2;+0:15]-[CH2;+0:14]-1)-[CH;+0:6](-[*:7])-[*:8]-[*:9]-[C;H0;+0:10]-3(-[CH;+0:11](-[*:12])-[*:13])-[O;H0;+0:18]-2.[*:17]-[OH;+0:16]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Structures and Biosynthesis of Corvol Ethers--Sesquiterpenes from the Actinomycete Kitasatospora setae.Rabe P, Pahirulzaman KA, Dickschat JS2015 May 1125809275
Lessons from 1,3-Hydride Shifts in Sesquiterpene Cyclizations.Rinkel J, Rabe P, Garbeva P, Dickschat JS2016 Oct 1727666571