EC number:4.2.3.180

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.180
Description:Pseudolaratriene synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.180
BRENDA Enzyme Link: BRENDA 4.2.3.180
KEGG Enzyme Link: KEGG4.2.3.180
BioCyc Enzyme Link: BioCyc 4.2.3.180
ExPASy Enzyme Link: ExPASy4.2.3.180
EC2PDB Enzyme Link: EC2PDB 4.2.3.180
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.180
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.180
IntEnz Enzyme Link: IntEnz 4.2.3.180
MEDLINE Enzyme Link: MEDLINE 4.2.3.180

EC number:4.2.3.180

MSA:

4.2.3.180;
Phylogenetic Tree:

4.2.3.180;
Uniprot:
M-CSA:
RHEA:54116 all-trans-geranylgeranyl diphosphate = diphosphate + pseudolaratriene
RULE(radius=1) ([*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[*:5]-[CH;+0:6]=[C;H0;+0:7](-[*:8])-[*:9]-[*:10]-[CH;+0:11]=[C;H0;+0:12](-[*:13])-[CH2;+0:14]-[*:15])>>[*:1]-[CH2;+0:2]-[C;H0;+0:7]1(-[*:8])-[*:9]-[*:10]-[CH;+0:11](-[C;H0;+0:12](-[*:13])=[CH;+0:14]-[*:15])-[CH;+0:6]-1-[*:5].[*:4]-[OH;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Biosynthesis of the microtubule-destabilizing diterpene pseudolaric acid B from golden larch involves an unusual diterpene synthase.Mafu S, Karunanithi PS, Palazzo TA, Harrod BL, Rodriguez SM, Mollhoff IN, O'Brien TE, Tong S, Fiehn O, Tantillo DJ, Bohlmann J, Zerbe P2017 Jan 3128096378