EC number:4.2.3.182

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.182
Description:Pristinol synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.182
BRENDA Enzyme Link: BRENDA 4.2.3.182
KEGG Enzyme Link: KEGG4.2.3.182
BioCyc Enzyme Link: BioCyc 4.2.3.182
ExPASy Enzyme Link: ExPASy4.2.3.182
EC2PDB Enzyme Link: EC2PDB 4.2.3.182
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.182
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.182
IntEnz Enzyme Link: IntEnz 4.2.3.182
MEDLINE Enzyme Link: MEDLINE 4.2.3.182

EC number:4.2.3.182

MSA:

4.2.3.182;
Phylogenetic Tree:

4.2.3.182;
Uniprot:
M-CSA:
RHEA:54372 (2E,6E)-farnesyl diphosphate + H2O = (+)-(2S,3R,9R)-pristinol + diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3]-[*:4]-[CH;+0:5]=[*:6]-[*:7]-[CH2;+0:8]-[CH;+0:9]=[C;H0;+0:10](-[*:11])-[*:12])=[CH;+0:13]-[CH2;+0:14]-[O;H0;+0:15]-[*:16].[OH2;+0:17]>>[*:1]-[CH;+0:2]1-[*:3]-[*:4]-[C;H0;+0:5]2=[*:6]-[*:7]-[CH;+0:8](-[OH;+0:17])-[CH2;+0:9]-[C;H0;+0:10](-[*:11])(-[*:12])-[CH2;+0:14]-[CH;+0:13]-2-1.[*:16]-[OH;+0:15]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Pristinol, a Sesquiterpene Alcohol with an Unusual Skeleton from Streptomyces pristinaespiralis.Klapschinski TA, Rabe P, Dickschat JS2016 Aug 1627403888