EC number:4.2.3.183

Enzyme

Download
EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.183
Description:Nezukol synthase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.183
BRENDA Enzyme Link: BRENDA 4.2.3.183
KEGG Enzyme Link: KEGG4.2.3.183
BioCyc Enzyme Link: BioCyc 4.2.3.183
ExPASy Enzyme Link: ExPASy4.2.3.183
EC2PDB Enzyme Link: EC2PDB 4.2.3.183
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.183
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.183
IntEnz Enzyme Link: IntEnz 4.2.3.183
MEDLINE Enzyme Link: MEDLINE 4.2.3.183

EC number:4.2.3.183

MSA:

4.2.3.183;
Phylogenetic Tree:

4.2.3.183;
Uniprot:
M-CSA:
RHEA:54376 (+)-copalyl diphosphate + H2O = diphosphate + nezukol
RULE(radius=1) ([*:1]-[C;H0;+0:2](-[*:3])=[CH2;+0:4].[*:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-[CH2;+0:9]-[O;H0;+0:10]-[*:11]).[OH2;+0:12]>>[*:5]-[C;H0;+0:6](-[*:7])(-[CH2;+0:4]-[C;H0;+0:2](-[*:1])(-[*:3])-[OH;+0:12])-[CH;+0:8]=[CH2;+0:9].[*:11]-[OH;+0:10]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Biosynthesis of the oxygenated diterpene nezukol in the medicinal plant Isodon rubescens is catalyzed by a pair of diterpene synthases.Pelot KA, Hagelthorn DM, Addison JB, Zerbe P201728445526