Enzyme

Download
EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.19
Description:Ent-kaurene synthase.
Alternative Name: Ent-kaurene synthetase B.
Ent-kaurene synthase B.
Cath: 1.10.600.10; 1.50.10.130; 1.50.10.160;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.19
BRENDA Enzyme Link: BRENDA 4.2.3.19
KEGG Enzyme Link: KEGG4.2.3.19
BioCyc Enzyme Link: BioCyc 4.2.3.19
ExPASy Enzyme Link: ExPASy4.2.3.19
EC2PDB Enzyme Link: EC2PDB 4.2.3.19
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.19
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.19
IntEnz Enzyme Link: IntEnz 4.2.3.19
MEDLINE Enzyme Link: MEDLINE 4.2.3.19
MSA:

4.2.3.19;

Phylogenetic Tree:

4.2.3.19;

Uniprot:
M-CSA:
RHEA:22220 ent-copalyl diphosphate = diphosphate + ent-kaur-16-ene
RULE(radius=1) ([*:1]-[C;H0;+0:2](-[*:3])=[CH2;+0:4].[*:5]-[C;H0;+0:6](-[CH3;+0:7])=[CH;+0:8]-[CH2;+0:9]-[O;H0;+0:10]-[*:11])>>[*:5]-[CH;+0:6]1-[CH2;+0:7]-[C;H0;+0:2](-[*:1])(-[*:3])-[CH2;+0:4]-[C;H0;+0:8]-1=[CH2;+0:9].[*:11]-[OH;+0:10]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Ent-kaurene synthase from the fungus Phaeosphaeria sp. L487. cDNA isolation, characterization, and bacterial expression of a bifunctional diterpene cyclase in fungal gibberellin biosynthesis.Kawaide H, Imai R, Sassa T, Kamiya Y1997 Aug 299268298
Cloning of a full-length cDNA encoding ent-kaurene synthase from Gibberella fujikuroi: functional analysis of a bifunctional diterpene cyclase.Toyomasu T, Kawaide H, Ishizaki A, Shinoda S, Otsuka M, Mitsuhashi W, Sassa T2000 Mar10803977
Molecular cloning and characterization of a cDNA encoding the gibberellin biosynthetic enzyme ent-kaurene synthase B from pumpkin (Cucurbita maxima L.).Yamaguchi S, Saito T, Abe H, Yamane H, Murofushi N, Kamiya Y1996 Aug8771778
A cDNA clone for taxadiene synthase, the diterpene cyclase that catalyzes the committed step of taxol biosynthesis.Wildung MR, Croteau R1996 Apr 198621577