ID: | 4.2.3.191 |
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Description: | Cycloaraneosene synthase. |
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 4.2.3.191 |
BRENDA Enzyme Link: | BRENDA 4.2.3.191 |
KEGG Enzyme Link: | KEGG4.2.3.191 |
BioCyc Enzyme Link: | BioCyc 4.2.3.191 |
ExPASy Enzyme Link: | ExPASy4.2.3.191 |
EC2PDB Enzyme Link: | EC2PDB 4.2.3.191 |
ExplorEnz Enzyme Link: | ExplorEnz 4.2.3.191 |
PRIAM enzyme-specific profiles Link: | PRIAM 4.2.3.191 |
IntEnz Enzyme Link: | IntEnz 4.2.3.191 |
MEDLINE Enzyme Link: | MEDLINE 4.2.3.191 |
MSA: | |
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Phylogenetic Tree: | |
Uniprot: | |
M-CSA: |
RHEA:54520 | all-trans-geranylgeranyl diphosphate = cycloaraneosene + diphosphate |
RULE(radius=1) | [*:1]-[C;H0;+0:2](-[*:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[CH3;+0:7])-[*:8]-[*:9]-[CH;+0:10]=[C;H0;+0:11](-[*:12])-[*:13]-[*:14]-[CH;+0:15]=[C;H0;+0:16](-[*:17])-[*:18])=[CH;+0:19]-[CH2;+0:20]-[O;H0;+0:21]-[*:22]>>[*:1]-[CH;+0:2]1-[*:3]-[*:4]-[CH;+0:5]2-[C;H0;+0:6](=[CH2;+0:7])-[*:8]-[*:9]-[C;H0;+0:10]3=[C;H0;+0:15](-[CH;+0:16](-[*:17])-[*:18])-[*:14]-[*:13]-[C;H0;+0:11]-3(-[*:12])-[CH2;+0:20]-[CH;+0:19]-1-2.[*:22]-[OH;+0:21] |
Reaction | ![]() |
Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
Title | Authors | Date | PubMed ID |
---|---|---|---|
Identification and characterization of bacterial diterpene cyclases that synthesize the cembrane skeleton. | Meguro A, Tomita T, Nishiyama M, Kuzuyama T | 2013 Feb 11 | 23386483 |