Enzyme

Download
EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.191
Description:Cycloaraneosene synthase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.191
BRENDA Enzyme Link: BRENDA 4.2.3.191
KEGG Enzyme Link: KEGG4.2.3.191
BioCyc Enzyme Link: BioCyc 4.2.3.191
ExPASy Enzyme Link: ExPASy4.2.3.191
EC2PDB Enzyme Link: EC2PDB 4.2.3.191
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.191
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.191
IntEnz Enzyme Link: IntEnz 4.2.3.191
MEDLINE Enzyme Link: MEDLINE 4.2.3.191
MSA:

4.2.3.191;

Phylogenetic Tree:

4.2.3.191;

Uniprot:
M-CSA:
RHEA:54520 all-trans-geranylgeranyl diphosphate = cycloaraneosene + diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[CH3;+0:7])-[*:8]-[*:9]-[CH;+0:10]=[C;H0;+0:11](-[*:12])-[*:13]-[*:14]-[CH;+0:15]=[C;H0;+0:16](-[*:17])-[*:18])=[CH;+0:19]-[CH2;+0:20]-[O;H0;+0:21]-[*:22]>>[*:1]-[CH;+0:2]1-[*:3]-[*:4]-[CH;+0:5]2-[C;H0;+0:6](=[CH2;+0:7])-[*:8]-[*:9]-[C;H0;+0:10]3=[C;H0;+0:15](-[CH;+0:16](-[*:17])-[*:18])-[*:14]-[*:13]-[C;H0;+0:11]-3(-[*:12])-[CH2;+0:20]-[CH;+0:19]-1-2.[*:22]-[OH;+0:21]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Identification and characterization of bacterial diterpene cyclases that synthesize the cembrane skeleton.Meguro A, Tomita T, Nishiyama M, Kuzuyama T2013 Feb 1123386483