EC number:4.2.3.21
| ID: | 4.2.3.21 |
|---|---|
| Description: | Vetispiradiene synthase. |
| Alternative Name: |
Vetispiradiene-forming farnesyl pyrophosphate cyclase. Vetispiradiene cyclase. Pemnaspirodiene synthase. HVS. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.3.21 |
| BRENDA Enzyme Link: | BRENDA 4.2.3.21 |
| KEGG Enzyme Link: | KEGG4.2.3.21 |
| BioCyc Enzyme Link: | BioCyc 4.2.3.21 |
| ExPASy Enzyme Link: | ExPASy4.2.3.21 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.3.21 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.3.21 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.3.21 |
| IntEnz Enzyme Link: | IntEnz 4.2.3.21 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.3.21 |
| RHEA:10340 | (2E,6E)-farnesyl diphosphate = (-)-vetispiradiene + diphosphate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[CH3;+0:3])=[CH;+0:4]-[*:5]-[*:6]-[C;H0;+0:7](-[CH3;+0:8])=[CH;+0:9]-[*:10]-[*:11]-[C;H0;+0:12](-[CH3;+0:13])=[CH;+0:14]-[CH2;+0:15]-[O;H0;+0:16]-[*:17]>>[*:1]-[C;H0;+0:2](=[CH2;+0:3])-[CH;+0:4]1-[*:5]-[*:6]-[C;H0;+0:7]2(-[CH2;+0:8]-1)-[C;H0;+0:14](-[CH3;+0:15])=[CH;+0:12]-[*:11]-[*:10]-[CH;+0:9]-2-[CH3;+0:13].[*:17]-[OH;+0:16] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase. | Starks CM, Back K, Chappell J, Noel JP | 1997 Sep 19 | 9295271 |
| Pre-steady-state study of recombinant sesquiterpene cyclases. | Mathis JR, Back K, Starks C, Noel J, Poulter CD, Chappell J | 1997 Jul 8 | 9204881 |
| Cloning and bacterial expression of a sesquiterpene cyclase from Hyoscyamus muticus and its molecular comparison to related terpene cyclases. | Back K, Chappell J | 1995 Mar 31 | 7706281 |
| The in vivo synthesis of plant sesquiterpenes by Escherichia coli. | Martin VJ, Yoshikuni Y, Keasling JD | 2001 Dec 5 | 11745124 |
| cDNA cloning of sesquiterpene cyclase and squalene synthase, and expression of the genes in potato tuber infected with Phytophthora infestans. | Yoshioka H, Yamada N, Doke N | 1999 Sep | 10588069 |