EC number:4.2.3.23
| ID: | 4.2.3.23 |
|---|---|
| Description: | Germacrene-A synthase. |
| Alternative Name: |
Germacrene A synthase. GAS. (+)-germacrene A synthase. (+)-(10R)-germacrene A synthase. |
| Cath: | 1.10.600.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.3.23 |
| BRENDA Enzyme Link: | BRENDA 4.2.3.23 |
| KEGG Enzyme Link: | KEGG4.2.3.23 |
| BioCyc Enzyme Link: | BioCyc 4.2.3.23 |
| ExPASy Enzyme Link: | ExPASy4.2.3.23 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.3.23 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.3.23 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.3.23 |
| IntEnz Enzyme Link: | IntEnz 4.2.3.23 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.3.23 |
| RHEA:12516 | (2E,6E)-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate |
| RULE(radius=1) | ([*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[*:5]-[CH;+0:6]=[C;H0;+0:7](-[*:8])-[CH3;+0:9])>>[*:1]-[CH2;+0:2]-[CH;+0:6](-[*:5])-[C;H0;+0:7](-[*:8])=[CH2;+0:9].[*:4]-[OH;+0:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| (+)-Germacrene A biosynthesis . The committed step in the biosynthesis of bitter sesquiterpene lactones in chicory | de Kraker JW, Franssen MC, de Groot A, Konig WA, Bouwmeester HJ | 1998 Aug | 9701594 |
| The organ-specific expression of terpene synthase genes contributes to the terpene hydrocarbon composition of chamomile essential oils. | Irmisch S, Krause ST, Kunert G, Gershenzon J, Degenhardt J, Köllner TG | 2012 Jun 8 | 22682202 |
| Identification, functional characterization and developmental regulation of sesquiterpene synthases from sunflower capitate glandular trichomes. | Göpfert JC, Macnevin G, Ro DK, Spring O | 2009 Jul 6 | 19580670 |
| The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases. | Deguerry F, Pastore L, Wu S, Clark A, Chappell J, Schalk M | 2006 Oct 15 | 16970904 |
| Isolation and characterization of two germacrene A synthase cDNA clones from chicory. | Bouwmeester HJ, Kodde J, Verstappen FW, Altug IG, de Kraker JW, Wallaart TE | 2002 May | 12011345 |