EC number:4.2.3.32
| ID: | 4.2.3.32 |
|---|---|
| Description: | Levopimaradiene synthase. |
| Cath: | 1.10.600.10; 1.50.10.130; 1.50.10.160; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.3.32 |
| BRENDA Enzyme Link: | BRENDA 4.2.3.32 |
| KEGG Enzyme Link: | KEGG4.2.3.32 |
| BioCyc Enzyme Link: | BioCyc 4.2.3.32 |
| ExPASy Enzyme Link: | ExPASy4.2.3.32 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.3.32 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.3.32 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.3.32 |
| IntEnz Enzyme Link: | IntEnz 4.2.3.32 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.3.32 |
| RHEA:25548 | (+)-copalyl diphosphate = abieta-8(14),12-diene + diphosphate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[C;H0;+0:3](=[CH2;+0:4])-[CH;+0:5](-[*:6])-[CH2;+0:7]-[CH2;+0:8]-[*:9](-[CH3;+0:10])=[*:11]-[CH2;+0:12]-[O;H0;+0:13]-[*:14]>>[*:1]-[CH2;+0:2]-[C;H0;+0:7]1=[CH;+0:8]-[*:9](-[CH;+0:10](-[CH3;+0:3])-[CH3;+0:4])=[*:11]-[CH2;+0:12]-[CH;+0:5]-1-[*:6].[*:14]-[OH;+0:13] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Evolution of conifer diterpene synthases: diterpene resin acid biosynthesis in lodgepole pine and jack pine involves monofunctional and bifunctional diterpene synthases. | Hall DE, Zerbe P, Jancsik S, Quesada AL, Dullat H, Madilao LL, Yuen M, Bohlmann J | 2013 Feb | 23370714 |
| Bifunctional cis-abienol synthase from Abies balsamea discovered by transcriptome sequencing and its implications for diterpenoid fragrance production. | Zerbe P, Chiang A, Yuen M, Hamberger B, Hamberger B, Draper JA, Britton R, Bohlmann J | 2012 Apr 6 | 22337889 |
| Diterpene resin acid biosynthesis in loblolly pine (Pinus taeda): functional characterization of abietadiene/levopimaradiene synthase (PtTPS-LAS) cDNA and subcellular targeting of PtTPS-LAS and abietadienol/abietadienal oxidase (PtAO, CYP720B1). | Ro DK, Bohlmann J | 2006 Aug | 16497345 |
| Cloning and characterization of Ginkgo biloba levopimaradiene synthase which catalyzes the first committed step in ginkgolide biosynthesis. | Schepmann HG, Pang J, Matsuda SP | 2001 Aug 15 | 11488601 |