| ID: | 4.2.3.37 |
|---|---|
| Description: | Epi-isozizaene synthase. |
| Cath: | 1.10.600.10; 1.10.630.10; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 4.2.3.37 |
| BRENDA Enzyme Link: | BRENDA 4.2.3.37 |
| KEGG Enzyme Link: | KEGG4.2.3.37 |
| BioCyc Enzyme Link: | BioCyc 4.2.3.37 |
| ExPASy Enzyme Link: | ExPASy4.2.3.37 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.3.37 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.3.37 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.3.37 |
| IntEnz Enzyme Link: | IntEnz 4.2.3.37 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.3.37 |
| RHEA:25992 | (2E,6E)-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[*:3])=[CH;+0:4]-[*:5]-[*:6]-[C;H0;+0:7](-[CH3;+0:8])=[CH;+0:9]-[*:10]-[*:11]-[C;H0;+0:12](-[CH3;+0:13])=[CH;+0:14]-[CH2;+0:15]-[O;H0;+0:16]-[*:17]>>[*:1]-[C;H0;+0:2]1(-[*:3])-[C;H0;+0:14](-[CH3;+0:15])=[C;H0;+0:12]2-[*:11]-[*:10]-[CH;+0:9](-[CH3;+0:13])-[C;H0;+0:7]-23-[*:6]-[*:5]-[CH;+0:4]-1-[CH2;+0:8]-3.[*:17]-[OH;+0:16] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor A3(2). | Zhao B, Lin X, Lei L, Lamb DC, Kelly SL, Waterman MR, Cane DE | 2008 Mar 28 | 18234666 |
| Genome mining in Streptomyces coelicolor: molecular cloning and characterization of a new sesquiterpene synthase. | Lin X, Hopson R, Cane DE | 2006 May 10 | 16669656 |