Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.43
Description:Fusicocca-2,10(14)-diene synthase.
Alternative Name: Fusicoccadiene synthase.
Prosite: PDOC00407;
PDB:
PDBScop
Cath: 1.10.600.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.43
BRENDA Enzyme Link: BRENDA 4.2.3.43
KEGG Enzyme Link: KEGG4.2.3.43
BioCyc Enzyme Link: BioCyc 4.2.3.43
ExPASy Enzyme Link: ExPASy4.2.3.43
EC2PDB Enzyme Link: EC2PDB 4.2.3.43
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.43
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.43
IntEnz Enzyme Link: IntEnz 4.2.3.43
MEDLINE Enzyme Link: MEDLINE 4.2.3.43
MSA:

4.2.3.43;

Phylogenetic Tree:

4.2.3.43;

Uniprot:
M-CSA:
RHEA:26245 geranylgeranyl diphosphate = diphosphate + fusicocca-2,10(14)-diene
RULE(radius=1) ([*:1]-[CH;+0:2]=[C;H0;+0:3](-[*:4])-[*:5]-[*:6]-[CH;+0:7]=[C;H0;+0:8](-[*:9])-[*:10]-[*:11]-[CH;+0:12]=[C;H0;+0:13](-[*:14])-[*:15].[*:16]=[CH;+0:17]-[CH2;+0:18]-[O;H0;+0:19]-[*:20])>>[*:20]-[OH;+0:19].[*:16]=[C;H0;+0:17]1-[CH2;+0:18]-[C;H0;+0:8]2(-[*:9])-[*:10]-[*:11]-[C;H0;+0:12](-[CH;+0:13](-[*:14])-[*:15])=[C;H0;+0:7]-2-[*:6]-[*:5]-[CH;+0:3](-[*:4])-[CH;+0:2]-1-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Identification and functional analysis of brassicicene C biosynthetic gene cluster in Alternaria brassicicola.Minami A, Tajima N, Higuchi Y, Toyomasu T, Sassa T, Kato N, Dairi T2009 Feb 119097780
Fusicoccins are biosynthesized by an unusual chimera diterpene synthase in fungi.Toyomasu T, Tsukahara M, Kaneko A, Niida R, Mitsuhashi W, Dairi T, Kato N, Sassa T2007 Feb 2717360612