EC number:4.2.3.61

Enzyme

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     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.61
Description:5-epiaristolochene synthase.
Alternative Name: Farnesyl pyrophosphate cyclase.
5-epi-aristolochene synthase.
Cath: 1.10.600.10; 1.50.10.130;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.61
BRENDA Enzyme Link: BRENDA 4.2.3.61
KEGG Enzyme Link: KEGG4.2.3.61
BioCyc Enzyme Link: BioCyc 4.2.3.61
ExPASy Enzyme Link: ExPASy4.2.3.61
EC2PDB Enzyme Link: EC2PDB 4.2.3.61
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.61
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.61
IntEnz Enzyme Link: IntEnz 4.2.3.61
MEDLINE Enzyme Link: MEDLINE 4.2.3.61

EC number:4.2.3.61

MSA:

4.2.3.61;
Phylogenetic Tree:

4.2.3.61;
Uniprot:
M-CSA:
RHEA:28635 (2E,6E)-farnesyl diphosphate = (+)-5-epi-aristolochene + diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[CH2;+0:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[CH3;+0:8])=[CH;+0:9]-[*:10]-[*:11]-[C;H0;+0:12](-[CH3;+0:13])=[*:14]-[CH2;+0:15]-[O;H0;+0:16]-[*:17]>>[*:1]-[CH;+0:2]1-[CH2;+0:9]-[*:10]-[*:11]-[C;H0;+0:12]2=[*:14]-[CH2;+0:15]-[CH;+0:5](-[C;H0;+0:6](-[*:7])=[CH2;+0:8])-[*:4]-[C;H0;+0:3]-2-1-[CH3;+0:13].[*:17]-[OH;+0:16]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Biosynthetic potential of sesquiterpene synthases: alternative products of tobacco 5-epi-aristolochene synthase.O'Maille PE, Chappell J, Noel JP2006 Apr 1516375847