EC number:4.2.3.67

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.67
Description:Cis-muuroladiene synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.67
BRENDA Enzyme Link: BRENDA 4.2.3.67
KEGG Enzyme Link: KEGG4.2.3.67
BioCyc Enzyme Link: BioCyc 4.2.3.67
ExPASy Enzyme Link: ExPASy4.2.3.67
EC2PDB Enzyme Link: EC2PDB 4.2.3.67
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.67
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.67
IntEnz Enzyme Link: IntEnz 4.2.3.67
MEDLINE Enzyme Link: MEDLINE 4.2.3.67

EC number:4.2.3.67

MSA:

4.2.3.67;
Phylogenetic Tree:

4.2.3.67;
Uniprot:
M-CSA:
RHEA:29491 (2E,6E)-farnesyl diphosphate = cis-muurola-4(14),5-diene + diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[*:8])=[CH;+0:9]-[*:10]-[*:11]-[C;H0;+0:12](-[CH3;+0:13])=[CH;+0:14]-[CH2;+0:15]-[O;H0;+0:16]-[*:17]>>[*:1]-[CH;+0:2]1-[*:3]-[*:4]-[CH;+0:5](-[CH;+0:6](-[*:7])-[*:8])-[C;H0;+0:15]2=[CH;+0:14]-[C;H0;+0:12](=[CH2;+0:13])-[*:11]-[*:10]-[CH;+0:9]-2-1.[*:17]-[OH;+0:16]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Cloning and functional characterisation of a cis-muuroladiene synthase from black peppermint (Menthaxpiperita) and direct evidence for a chemotype unable to synthesise farnesene.Prosser IM, Adams RJ, Beale MH, Hawkins ND, Phillips AL, Pickett JA, Field LM2006 Aug16083926
RHEA:29487 (2E,6E)-farnesyl diphosphate = cis-muurola-3,5-diene + diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[*:8])=[CH;+0:9]-[CH2;+0:10]-[CH2;+0:11]-[*:12]=[*:13]-[CH2;+0:14]-[O;H0;+0:15]-[*:16]>>[*:1]-[CH;+0:2]1-[*:3]-[*:4]-[CH;+0:5](-[CH;+0:6](-[*:7])-[*:8])-[C;H0;+0:10]2=[CH;+0:11]-[*:12]=[*:13]-[CH2;+0:14]-[CH;+0:9]-2-1.[*:16]-[OH;+0:15]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Cloning and functional characterisation of a cis-muuroladiene synthase from black peppermint (Menthaxpiperita) and direct evidence for a chemotype unable to synthesise farnesene.Prosser IM, Adams RJ, Beale MH, Hawkins ND, Phillips AL, Pickett JA, Field LM2006 Aug16083926