EC number:4.2.3.70
| ID: | 4.2.3.70 |
|---|---|
| Description: | Patchoulol synthase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.2.3.70 |
| BRENDA Enzyme Link: | BRENDA 4.2.3.70 |
| KEGG Enzyme Link: | KEGG4.2.3.70 |
| BioCyc Enzyme Link: | BioCyc 4.2.3.70 |
| ExPASy Enzyme Link: | ExPASy4.2.3.70 |
| EC2PDB Enzyme Link: | EC2PDB 4.2.3.70 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.2.3.70 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.2.3.70 |
| IntEnz Enzyme Link: | IntEnz 4.2.3.70 |
| MEDLINE Enzyme Link: | MEDLINE 4.2.3.70 |
| RHEA:29503 | (2E,6E)-farnesyl diphosphate + H2O = diphosphate + patchoulol |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[*:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[*:8]-[*:9]-[CH;+0:10]=[C;H0;+0:11](-[*:12])-[*:13])=[CH;+0:14]-[CH2;+0:15]-[O;H0;+0:16]-[*:17].[OH2;+0:18]>>[*:1]-[CH;+0:2]1-[*:3]-[*:4]-[C;H0;+0:5]2(-[OH;+0:18])-[C;H0;+0:6]3(-[*:7])-[*:8]-[*:9]-[CH;+0:10](-[CH2;+0:15]-[CH;+0:14]-1-3)-[C;H0;+0:11]-2(-[*:12])-[*:13].[*:17]-[OH;+0:16] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Biosynthesis of the sesquiterpene patchoulol from farnesyl pyrophosphate in leaf extracts of Pogostemon cablin (patchouli): mechanistic considerations. | Croteau R, Munck SL, Akoh CC, Fisk HJ, Satterwhite DM | 1987 Jul | 3038029 |
| Purification and characterization of the sesquiterpene cyclase patchoulol synthase from Pogostemon cablin. | Munck SL, Croteau R | 1990 Oct | 2171435 |
| Doubly deuterium-labeled patchouli alcohol from cyclization of singly labeled [2-(2)H(1)]farnesyl diphosphate catalyzed by recombinant patchoulol synthase. | Faraldos JA, Wu S, Chappell J, Coates RM | 2010 Mar 10 | 20148554 |