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4. Lyases

4.2 Carbon-oxygen lyases

4.2.3 Acting on phosphates

ID:	4.2.3.87
Description:	Alpha-guaiene synthase.

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UniProtKB Enzyme Link:	UniProtKB 4.2.3.87
BRENDA Enzyme Link:	BRENDA 4.2.3.87
KEGG Enzyme Link:	KEGG4.2.3.87
BioCyc Enzyme Link:	BioCyc 4.2.3.87
ExPASy Enzyme Link:	ExPASy4.2.3.87
EC2PDB Enzyme Link:	EC2PDB 4.2.3.87
ExplorEnz Enzyme Link:	ExplorEnz 4.2.3.87
PRIAM enzyme-specific profiles Link:	PRIAM 4.2.3.87
IntEnz Enzyme Link:	IntEnz 4.2.3.87
MEDLINE Enzyme Link:	MEDLINE 4.2.3.87

RHEA:31807	(2E,6E)-farnesyl diphosphate = alpha-guaiene + diphosphate
RULE(radius=1)	[:1]-[C;H0;+0:2](-[:3]-[:4]-[CH;+0:5]=[C;H0;+0:6](-[:7])-[:8]-[:9]-[CH;+0:10]=[C;H0;+0:11](-[:12])-[CH3;+0:13])=[CH;+0:14]-[CH2;+0:15]-[O;H0;+0:16]-[:17]>>[:1]-[CH;+0:2]1-[:3]-[:4]-[C;H0;+0:5]2=[C;H0;+0:14]-1-[CH2;+0:15]-[CH;+0:10](-[C;H0;+0:11](-[:12])=[CH2;+0:13])-[:9]-[:8]-[CH;+0:6]-2-[:7].[:17]-[OH;+0:16]
Reaction
Core-to-Core	No scaffolds atoms were exchanged as a result of the reaction

Title	Authors	Date	PubMed ID
Sesquiterpene synthases from grand fir (Abies grandis). Comparison of constitutive and wound-induced activities, and cDNA isolation, characterization, and bacterial expression of delta-selinene synthase and gamma-humulene synthase.	Steele CL, Crock J, Bohlmann J, Croteau R	1998 Jan 23	9442047
The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases.	Deguerry F, Pastore L, Wu S, Clark A, Chappell J, Schalk M	2006 Oct 15	16970904
Characterization of delta-guaiene synthases from cultured cells of Aquilaria, responsible for the formation of the sesquiterpenes in agarwood.	Kumeta Y, Ito M	2010 Dec	20959422