EC number:4.2.3.96

Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.3 Acting on phosphates
ID:4.2.3.96
Description:Avermitilol synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.3.96
BRENDA Enzyme Link: BRENDA 4.2.3.96
KEGG Enzyme Link: KEGG4.2.3.96
BioCyc Enzyme Link: BioCyc 4.2.3.96
ExPASy Enzyme Link: ExPASy4.2.3.96
EC2PDB Enzyme Link: EC2PDB 4.2.3.96
ExplorEnz Enzyme Link: ExplorEnz 4.2.3.96
PRIAM enzyme-specific profiles Link: PRIAM 4.2.3.96
IntEnz Enzyme Link: IntEnz 4.2.3.96
MEDLINE Enzyme Link: MEDLINE 4.2.3.96

EC number:4.2.3.96

MSA:

4.2.3.96;
Phylogenetic Tree:

4.2.3.96;
Uniprot:
M-CSA:
RHEA:32023 (2E,6E)-farnesyl diphosphate + H2O = avermitilol + diphosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3]-[*:4]-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[*:8]-[*:9]-[CH;+0:10]=[C;H0;+0:11](-[*:12])-[*:13])=[CH;+0:14]-[CH2;+0:15]-[O;H0;+0:16]-[*:17].[OH2;+0:18]>>[*:1]-[CH;+0:2]1-[*:3]-[*:4]-[CH;+0:5](-[OH;+0:18])-[C;H0;+0:6]2(-[*:7])-[*:8]-[*:9]-[CH;+0:10]3-[CH;+0:15](-[CH;+0:14]-1-2)-[C;H0;+0:11]-3(-[*:12])-[*:13].[*:17]-[OH;+0:16]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Genome mining in Streptomyces avermitilis: cloning and characterization of SAV_76, the synthase for a new sesquiterpene, avermitilol.Chou WK, Fanizza I, Uchiyama T, Komatsu M, Ikeda H, Cane DE2010 Jul 720536237