EC number:4.3.1.15
| ID: | 4.3.1.15 |
|---|---|
| Description: | Diaminopropionate ammonia-lyase. |
| Alternative Name: |
Diaminopropionatase. Alpha,beta-diaminopropionate ammonia-lyase. 2,3-diaminopropanoate ammonia-lyase. |
| Cath: | 3.40.50.1100; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.3.1.15 |
| BRENDA Enzyme Link: | BRENDA 4.3.1.15 |
| KEGG Enzyme Link: | KEGG4.3.1.15 |
| BioCyc Enzyme Link: | BioCyc 4.3.1.15 |
| ExPASy Enzyme Link: | ExPASy4.3.1.15 |
| EC2PDB Enzyme Link: | EC2PDB 4.3.1.15 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.3.1.15 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.3.1.15 |
| IntEnz Enzyme Link: | IntEnz 4.3.1.15 |
| MEDLINE Enzyme Link: | MEDLINE 4.3.1.15 |
| RHEA:52432 | (R)-2,3-diaminopropanoate + H(+) + H2O = 2 NH4(+) + pyruvate |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[NH2;+0:3])-[CH2;+0:4]-[NH2;+0:5].[H+;H0:6].[OH2;+0:7]>>[*:1]-[C;H0;+0:2](-[CH3;+0:4])=[O;H0;+0:7].[NH3;+0:3].[NH3;+0:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Diaminopropionate ammonia-lyase from Salmonella typhimurium. Purification and characterization of the crystalline enzyme, and sequence determination of the pyridoxal 5'-phosphate binding peptide. | Nagasawa T, Tanizawa K, Satoda T, Yamada H | 1988 Jan 15 | 3275662 |
| Crystal structure of Escherichia coli diaminopropionate ammonia-lyase reveals mechanism of enzyme activation and catalysis. | Bisht S, Rajaram V, Bharath SR, Kalyani JN, Khan F, Rao AN, Savithri HS, Murthy MR | 2012 Jun 8 | 22505717 |
| RHEA:22084 | (S)-2,3-diaminopropanoate + H(+) + H2O = 2 NH4(+) + pyruvate |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[NH2;+0:3])-[CH2;+0:4]-[NH2;+0:5].[H+;H0:6].[OH2;+0:7]>>[*:1]-[C;H0;+0:2](-[CH3;+0:4])=[O;H0;+0:7].[NH3;+0:3].[NH3;+0:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Diaminopropionate ammonia-lyase from Salmonella typhimurium. Purification and characterization of the crystalline enzyme, and sequence determination of the pyridoxal 5'-phosphate binding peptide. | Nagasawa T, Tanizawa K, Satoda T, Yamada H | 1988 Jan 15 | 3275662 |
| Crystal structure of Escherichia coli diaminopropionate ammonia-lyase reveals mechanism of enzyme activation and catalysis. | Bisht S, Rajaram V, Bharath SR, Kalyani JN, Khan F, Rao AN, Savithri HS, Murthy MR | 2012 Jun 8 | 22505717 |