EC number:4.3.1.17
| ID: | 4.3.1.17 | ||
|---|---|---|---|
| Description: | L-serine ammonia-lyase. | ||
| Alternative Name: |
Serine deaminase. L-serine hydro-lyase (deaminating). L-serine dehydratase. L-serine deaminase. L-hydroxyaminoacid dehydratase. | ||
| Prosite: | PDOC00149; | ||
| PDB: |
|
||
| Cath: | 3.30.1330.40; 3.30.1330.90; 3.40.1020.10; 3.40.50.1100; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.3.1.17 |
| BRENDA Enzyme Link: | BRENDA 4.3.1.17 |
| KEGG Enzyme Link: | KEGG4.3.1.17 |
| BioCyc Enzyme Link: | BioCyc 4.3.1.17 |
| ExPASy Enzyme Link: | ExPASy4.3.1.17 |
| EC2PDB Enzyme Link: | EC2PDB 4.3.1.17 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.3.1.17 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.3.1.17 |
| IntEnz Enzyme Link: | IntEnz 4.3.1.17 |
| MEDLINE Enzyme Link: | MEDLINE 4.3.1.17 |
| RHEA:19169 | L-serine = NH4(+) + pyruvate |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[NH2;+0:3])-[CH2;+0:4]-[OH;+0:5]>>[*:1]-[C;H0;+0:2](-[CH3;+0:4])=[O;H0;+0:5].[NH3;+0:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Crystal structure of a homolog of mammalian serine racemase from Schizosaccharomyces pombe. | Goto M, Yamauchi T, Kamiya N, Miyahara I, Yoshimura T, Mihara H, Kurihara T, Hirotsu K, Esaki N | 2009 Sep 18 | 19640845 |
| Crystal structure of serine dehydratase from rat liver. | Yamada T, Komoto J, Takata Y, Ogawa H, Pitot HC, Takusagawa F | 2003 Nov 11 | 14596599 |
| A catalytic mechanism that explains a low catalytic activity of serine dehydratase like-1 from human cancer cells: crystal structure and site-directed mutagenesis studies. | Yamada T, Komoto J, Kasuya T, Takata Y, Ogawa H, Mori H, Takusagawa F | 2008 May | 18342636 |