EC number:4.3.3.2
| ID: | 4.3.3.2 |
|---|---|
| Description: | Strictosidine synthase. |
| Alternative Name: |
Strictosidine synthetase. STR. |
| Cath: | 2.120.10.30; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.3.3.2 |
| BRENDA Enzyme Link: | BRENDA 4.3.3.2 |
| KEGG Enzyme Link: | KEGG4.3.3.2 |
| BioCyc Enzyme Link: | BioCyc 4.3.3.2 |
| ExPASy Enzyme Link: | ExPASy4.3.3.2 |
| EC2PDB Enzyme Link: | EC2PDB 4.3.3.2 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.3.3.2 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.3.3.2 |
| IntEnz Enzyme Link: | IntEnz 4.3.3.2 |
| MEDLINE Enzyme Link: | MEDLINE 4.3.3.2 |
| RHEA:15013 | 3alpha(S)-strictosidine + H2O = secologanin + tryptamine |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[NH;+0:3]-[*:4])-[c;H0;+0:5](:[*:6]):[*:7].[OH2;+0:8]>>[*:1]-[CH;+0:2]=[O;H0;+0:8].([*:4]-[NH2;+0:3].[*:6]:[cH;+0:5]:[*:7]) |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Strictosidine synthase from Catharanthus roseus: purification and characterization of multiple forms. | de Waal A, Meijer AH, Verpoorte R | 1995 Mar 1 | 7887913 |
| Strictosidine: from alkaloid to enzyme to gene. | Kutchan TM | 1993 Feb | 7763429 |
| 3D-Structure and function of strictosidine synthase--the key enzyme of monoterpenoid indole alkaloid biosynthesis. | Stöckigt J, Barleben L, Panjikar S, Loris EA | 2008 Mar | 18280746 |
| The structure of Rauvolfia serpentina strictosidine synthase is a novel six-bladed beta-propeller fold in plant proteins. | Ma X, Panjikar S, Koepke J, Loris E, Stöckigt J | 2006 Apr | 16531499 |
| Substrate specificity of strictosidine synthase. | McCoy E, Galan MC, O'Connor SE | 2006 May 1 | 16481164 |
| Functional expression of an ajmaline pathway-specific esterase from Rauvolfia in a novel plant-virus expression system. | Ruppert M, Woll J, Giritch A, Genady E, Ma X, Stöckigt J | 2005 Nov | 16133216 |