Enzyme

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     4. Lyases
        4.4 Carbon-sulfur lyases
            4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)
ID:4.4.1.19
Description:Phosphosulfolactate synthase.
Alternative Name: PSL synthase.
(2R)-phospho-3-sulfolactate synthase.
Cath: 3.20.20.70;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 4.4.1.19
BRENDA Enzyme Link: BRENDA 4.4.1.19
KEGG Enzyme Link: KEGG4.4.1.19
BioCyc Enzyme Link: BioCyc 4.4.1.19
ExPASy Enzyme Link: ExPASy4.4.1.19
EC2PDB Enzyme Link: EC2PDB 4.4.1.19
ExplorEnz Enzyme Link: ExplorEnz 4.4.1.19
PRIAM enzyme-specific profiles Link: PRIAM 4.4.1.19
IntEnz Enzyme Link: IntEnz 4.4.1.19
MEDLINE Enzyme Link: MEDLINE 4.4.1.19
MSA:

4.4.1.19;

Phylogenetic Tree:

4.4.1.19;

Uniprot:
M-CSA:
RHEA:22784 (2R)-O-phospho-3-sulfolactate = H(+) + phosphoenolpyruvate + sulfite
RULE(radius=1) [*:1]=[S;H0;+0:2](-[*:3])(=[O;H0;+0:4])-[CH2;+0:5]-[CH;+0:6](-[*:7])-[*:8]>>[*:7]-[C;H0;+0:6](-[*:8])=[CH2;+0:5].[*:1]=[S;H0;+0:2](-[*:3])-[OH;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The structural determination of phosphosulfolactate synthase from Methanococcus jannaschii at 1.7-A resolution: an enolase that is not an enolase.Wise EL, Graham DE, White RH, Rayment I2003 Nov 1412952952
Identification of coenzyme M biosynthetic phosphosulfolactate synthase: a new family of sulfonate-biosynthesizing enzymes.Graham DE, Xu H, White RH2002 Apr 1911830598