Enzyme

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EC Tree
     4. Lyases
        4.4 Carbon-sulfur lyases
            4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)
ID:4.4.1.22
Description:S-(hydroxymethyl)glutathione synthase.
Alternative Name: Glutathione-dependent formaldehyde-activating enzyme.
Cath: 3.40.50.720; 3.90.1590.10; 3.90.180.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 4.4.1.22
BRENDA Enzyme Link: BRENDA 4.4.1.22
KEGG Enzyme Link: KEGG4.4.1.22
BioCyc Enzyme Link: BioCyc 4.4.1.22
ExPASy Enzyme Link: ExPASy4.4.1.22
EC2PDB Enzyme Link: EC2PDB 4.4.1.22
ExplorEnz Enzyme Link: ExplorEnz 4.4.1.22
PRIAM enzyme-specific profiles Link: PRIAM 4.4.1.22
IntEnz Enzyme Link: IntEnz 4.4.1.22
MEDLINE Enzyme Link: MEDLINE 4.4.1.22
MSA:

4.4.1.22;

Phylogenetic Tree:

4.4.1.22;

Uniprot:
M-CSA:
RHEA:22488 S-(hydroxymethyl)glutathione = formaldehyde + glutathione
RULE(radius=1) [*:1]-[S;H0;+0:2]-[CH2;+0:3]-[OH;+0:4]>>[*:1]-[SH;+0:2].[CH2;+0:3]=[O;H0;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction