EC number:4.4.1.26
Enzyme
Download| EC Tree |
| 4. Lyases |
| 4.4 Carbon-sulfur lyases |
| 4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date) |
| ID: | 4.4.1.26 |
|---|---|
| Description: | Olivetolic acid cyclase. |
| Cath: | 3.30.70.100; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 4.4.1.26 |
| BRENDA Enzyme Link: | BRENDA 4.4.1.26 |
| KEGG Enzyme Link: | KEGG4.4.1.26 |
| BioCyc Enzyme Link: | BioCyc 4.4.1.26 |
| ExPASy Enzyme Link: | ExPASy4.4.1.26 |
| EC2PDB Enzyme Link: | EC2PDB 4.4.1.26 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.4.1.26 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.4.1.26 |
| IntEnz Enzyme Link: | IntEnz 4.4.1.26 |
| MEDLINE Enzyme Link: | MEDLINE 4.4.1.26 |
| RHEA:34123 | 3,5,7-trioxododecanoyl-CoA = CoA + H(+) + olivetolate |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[CH2;+0:3]-[C;H0;+0:4](=[O;H0;+0:5])-[CH2;+0:6]-[C;H0;+0:7](=[O;H0;+0:8])-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[O;H0;+0:12])-[S;H0;+0:13]-[*:14]>>[*:14]-[SH;+0:13].[*:1]=[C;H0;+0:2](-[OH;+0:12])-[c;H0;+0:3]1:[c;H0;+0:4](-[OH;+0:5]):[cH;+0:6]:[c;H0;+0:7](-[OH;+0:8]):[cH;+0:9]:[c;H0;+0:10]:1-[*:11] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Identification of olivetolic acid cyclase from Cannabis sativa reveals a unique catalytic route to plant polyketides. | Gagne SJ, Stout JM, Liu E, Boubakir Z, Clark SM, Page JE | 2012 Jul 31 | 22802619 |
| Characterization of olivetol synthase, a polyketide synthase putatively involved in cannabinoid biosynthetic pathway. | Taura F, Tanaka S, Taguchi C, Fukamizu T, Tanaka H, Shoyama Y, Morimoto S | 2009 Jun 18 | 19454282 |