Enzyme

Download
EC Tree
     4. Lyases
        4.6 Phosphorus-oxygen lyases
            4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
ID:4.6.1.12
Description:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.
Alternative Name: MECDP-synthase.
Prosite: PDOC01048;
PDB:
PDBScop
1W57 8030891; 8030893; 8043270; 8043272;
1W55 8030891; 8030893; 8043270; 8043272;
1IV4 8030110; 8042489; 8030110; 8042489; 8030110; 8042489; 8030110; 8042489; 8030110; 8042489; 8030110; 8042489;
1IV3 8030110; 8042489; 8030110; 8042489; 8030110; 8042489; 8030110; 8042489; 8030110; 8042489; 8030110; 8042489;
1IV2 8030110; 8042489; 8030110; 8042489; 8030110; 8042489; 8030110; 8042489; 8030110; 8042489; 8030110; 8042489;
 » show all

Cath: 3.30.1330.50; 3.90.550.10;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.6.1.12
BRENDA Enzyme Link: BRENDA 4.6.1.12
KEGG Enzyme Link: KEGG4.6.1.12
BioCyc Enzyme Link: BioCyc 4.6.1.12
ExPASy Enzyme Link: ExPASy4.6.1.12
EC2PDB Enzyme Link: EC2PDB 4.6.1.12
ExplorEnz Enzyme Link: ExplorEnz 4.6.1.12
PRIAM enzyme-specific profiles Link: PRIAM 4.6.1.12
IntEnz Enzyme Link: IntEnz 4.6.1.12
MEDLINE Enzyme Link: MEDLINE 4.6.1.12
MSA:

4.6.1.12;

Phylogenetic Tree:

4.6.1.12;

Uniprot:
M-CSA:
RHEA:23864 4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP
RULE(radius=1) ([*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[*:7]-[OH;+0:8])>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[O;H0;+0:8]-[*:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction