EC Tree |
4. Lyases |
4.6 Phosphorus-oxygen lyases |
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date) |
ID: | 4.6.1.17 |
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Description: | Cyclic pyranopterin monophosphate synthase. |
Cath: | 3.30.70.640; |
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 4.6.1.17 |
BRENDA Enzyme Link: | BRENDA 4.6.1.17 |
KEGG Enzyme Link: | KEGG4.6.1.17 |
BioCyc Enzyme Link: | BioCyc 4.6.1.17 |
ExPASy Enzyme Link: | ExPASy4.6.1.17 |
EC2PDB Enzyme Link: | EC2PDB 4.6.1.17 |
ExplorEnz Enzyme Link: | ExplorEnz 4.6.1.17 |
PRIAM enzyme-specific profiles Link: | PRIAM 4.6.1.17 |
IntEnz Enzyme Link: | IntEnz 4.6.1.17 |
MEDLINE Enzyme Link: | MEDLINE 4.6.1.17 |
RHEA:49580 | (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate |
RULE(radius=1) | |
Reaction | ![]() |
Core-to-Core |
Title | Authors | Date | PubMed ID |
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Mechanism of pyranopterin ring formation in molybdenum cofactor biosynthesis. | Hover BM, Tonthat NK, Schumacher MA, Yokoyama K | 2015 May 19 | 25941396 |
C-Terminal glycine-gated radical initiation by GTP 3',8-cyclase in the molybdenum cofactor biosynthesis. | Hover BM, Yokoyama K | 2015 Mar 11 | 25697423 |
Identification of a cyclic nucleotide as a cryptic intermediate in molybdenum cofactor biosynthesis. | Hover BM, Loksztejn A, Ribeiro AA, Yokoyama K | 2013 May 8 | 23627491 |
Rearrangement reactions in the biosynthesis of molybdopterin--an NMR study with multiply 13C/15N labelled precursors. | Rieder C, Eisenreich W, O'Brien J, Richter G, Götze E, Boyle P, Blanchard S, Bacher A, Simon H | 1998 Jul 1 | 9692897 |
Investigation of the early steps of molybdopterin biosynthesis in Escherichia coli through the use of in vivo labeling studies. | Wuebbens MM, Rajagopalan KV | 1995 Jan 20 | 7836363 |
The tetrahydropyranopterin structure of the sulfur-free and metal-free molybdenum cofactor precursor. | Santamaria-Araujo JA, Fischer B, Otte T, Nimtz M, Mendel RR, Wray V, Schwarz G | 2004 Apr 16 | 14761975 |