| EC Tree |
| 4. Lyases |
| 4.99 Other lyases |
| 4.99.1 Sole sub-subclass for lyases that do not belong in the other subclasses |
| ID: | 4.99.1.11 |
|---|---|
| Description: | Sirohydrochlorin nickelchelatase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 4.99.1.11 |
| BRENDA Enzyme Link: | BRENDA 4.99.1.11 |
| KEGG Enzyme Link: | KEGG4.99.1.11 |
| BioCyc Enzyme Link: | BioCyc 4.99.1.11 |
| ExPASy Enzyme Link: | ExPASy4.99.1.11 |
| EC2PDB Enzyme Link: | EC2PDB 4.99.1.11 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.99.1.11 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.99.1.11 |
| IntEnz Enzyme Link: | IntEnz 4.99.1.11 |
| MEDLINE Enzyme Link: | MEDLINE 4.99.1.11 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:52796 | 2 H(+) + Ni-sirohydrochlorin = Ni(2+) + sirohydrochlorin |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[C;H0;+0:3](-[*:4])-[C;H0;+0:5]2=[N+;H0:6]3-[C;H0;+0:7]-1=[CH;+0:8]-[*:9]:[n;H0;+0:10]1:[*:11]-[CH;+0:12]=[C;H0;+0:13]4-[*:14]-[*:15]-[C;H0;+0:16]5=[N+;H0:17]-4-[Ni-2;H0:18]-3-1-[N;H0;+0:19]1-[C;H0;+0:20](=[CH;+0:21]-5)-[*:22]-[*:23]-[C;H0;+0:24]-1=[CH;+0:25]-2.[H+;H0:26].[H+;H0:27]>>[*:1]-[c;H0;+0:2]1:[c;H0;+0:3](-[*:4]):[c;H0;+0:5]2:[cH;+0:25]:[c;H0;+0:24]3:[nH;+0:19]:[c;H0;+0:20](:[cH;+0:21]:[c;H0;+0:16]4:[n;H0;+0:17]:[c;H0;+0:13](:[cH;+0:12]:[*:11]:[nH;+0:10]:[*:9]:[cH;+0:8]:[c;H0;+0:7]:1:[n;H0;+0:6]:2)-[*:14]-[*:15]-4)-[*:22]-[*:23]-3.[Ni+2;H0:18] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Elucidation of the biosynthesis of the methane catalyst coenzyme F<sub>430</sub>. | Moore SJ, Sowa ST, Schuchardt C, Deery E, Lawrence AD, Ramos JV, Billig S, Birkemeyer C, Chivers PT, Howard MJ, Rigby SE, Layer G, Warren MJ | 2017 Mar 2 | 28225763 |
| The biosynthetic pathway of coenzyme F430 in methanogenic and methanotrophic archaea. | Zheng K, Ngo PD, Owens VL, Yang XP, Mansoorabadi SO | 2016 Oct 21 | 27846569 |