3D structure

Click one PDB to see exact 3D structure provided by NGL.

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References

External Links

UniProtKB Enzyme Link: UniProtKB 5.1.1.1
BRENDA Enzyme Link: BRENDA 5.1.1.1
KEGG Enzyme Link: KEGG5.1.1.1
BioCyc Enzyme Link: BioCyc 5.1.1.1
ExPASy Enzyme Link: ExPASy5.1.1.1
EC2PDB Enzyme Link: EC2PDB 5.1.1.1
ExplorEnz Enzyme Link: ExplorEnz 5.1.1.1
PRIAM enzyme-specific profiles Link: PRIAM 5.1.1.1
IntEnz Enzyme Link: IntEnz 5.1.1.1
MEDLINE Enzyme Link: MEDLINE 5.1.1.1
MSA:

5.1.1.1;

Phylogenetic Tree:

5.1.1.1;

Uniprot:
M-CSA:
RHEA:20249 L-alanine = D-alanine
RULE(radius=1)
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Structural basis for the broad specificity of a new family of amino-acid racemases.Espaillat A, Carrasco-López C, Bernardo-García N, Pietrosemoli N, Otero LH, Álvarez L, de Pedro MA, Pazos F, Davis BM, Waldor MK, Hermoso JA, Cava F2014 Jan24419381
Thermolabile alanine racemase from a psychotroph, Pseudomonas fluorescens: purification and properties.Yokoigawa K, Kawai H, Endo K, Lim YH, Esaki N, Soda K1993 Jan7763424
Catabolic alanine racemase from Salmonella typhimurium: DNA sequence, enzyme purification, and characterization.Wasserman SA, Daub E, Grisafi P, Botstein D, Walsh CT1984 Oct 236391537
Biosynthetic alanine racemase of Salmonella typhimurium: purification and characterization of the enzyme encoded by the alr gene.Esaki N, Walsh CT1986 Jun 33524677
Expression, purification, and characterization of alanine racemase from Pseudomonas putida YZ-26.Liu JL, Liu XQ, Shi YW2012 Jan22806802
Structural features and kinetic characterization of alanine racemase from Staphylococcus aureus (Mu50).Scaletti ER, Luckner SR, Krause KL2012 Jan22194336
A periplasmic, pyridoxal-5'-phosphate-dependent amino acid racemase in Pseudomonas taetrolens.Matsui D, Oikawa T, Arakawa N, Osumi S, Lausberg F, Stäbler N, Freudl R, Eggeling L2009 Jul19300994
Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis.Wu D, Hu T, Zhang L, Chen J, Du J, Ding J, Jiang H, Shen X2008 Jun18434499
Site-directed mutagenesis of Tyr354 in Geobacillus stearothermophilus alanine racemase identifies a role in controlling substrate specificity and a possible role in the evolution of antibiotic resistance.Patrick WM, Weisner J, Blackburn JM2002 Aug 212203980
Gene cloning and characterization of alanine racemases from Shigella dysenteriae, Shigella boydii, Shigella flexneri, and Shigella sonnei.Yokoigawa K, Hirasawa R, Ueno H, Okubo Y, Umesako S, Soda K2001 Nov 211676496
Characterization of the alanine racemases from two mycobacteria.Strych U, Penland RL, Jimenez M, Krause KL, Benedik MJ2001 Mar 1511267762
Characterization of the alanine racemases from Pseudomonas aeruginosa PAO1.Strych U, Huang HC, Krause KL, Benedik MJ2000 Oct10977898
Serine and alanine racemase activities of VanT: a protein necessary for vancomycin resistance in Enterococcus gallinarum BM4174.Arias CA, Weisner J, Blackburn JM, Reynolds PE2000 Jul10878136
A eukaryotic alanine racemase gene involved in cyclic peptide biosynthesis.Cheng YQ, Walton JD2000 Feb 1810671527
Characterization of psychrophilic alanine racemase from Bacillus psychrosaccharolyticus.Okubo Y, Yokoigawa K, Esaki N, Soda K, Kawai H1999 Mar 1610080917
Structure of a Michaelis complex analogue: propionate binds in the substrate carboxylate site of alanine racemase.Morollo AA, Petsko GA, Ringe D1999 Mar 1610079072