| EC Tree |
| 5. Isomerases |
| 5.1 Racemases and epimerases |
| 5.1.1 Acting on amino acids and derivatives |
| ID: | 5.1.1.22 |
|---|---|
| Description: | 4-hydroxyproline betaine 2-epimerase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 5.1.1.22 |
| BRENDA Enzyme Link: | BRENDA 5.1.1.22 |
| KEGG Enzyme Link: | KEGG5.1.1.22 |
| BioCyc Enzyme Link: | BioCyc 5.1.1.22 |
| ExPASy Enzyme Link: | ExPASy5.1.1.22 |
| EC2PDB Enzyme Link: | EC2PDB 5.1.1.22 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.1.1.22 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.1.1.22 |
| IntEnz Enzyme Link: | IntEnz 5.1.1.22 |
| MEDLINE Enzyme Link: | MEDLINE 5.1.1.22 |
| RHEA:51884 | L-proline betaine = D-proline betaine |
| RULE(radius=1) | |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine. | Kumar R, Zhao S, Vetting MW, Wood BM, Sakai A, Cho K, Solbiati J, Almo SC, Sweedler JV, Jacobson MP, Gerlt JA, Cronan JE | 2014 Feb 11 | 24520058 |
| Discovery of new enzymes and metabolic pathways by using structure and genome context. | Zhao S, Kumar R, Sakai A, Vetting MW, Wood BM, Brown S, Bonanno JB, Hillerich BS, Seidel RD, Babbitt PC, Almo SC, Sweedler JV, Gerlt JA, Cronan JE, Jacobson MP | 2013 Oct 31 | 24056934 |
| RHEA:47544 | trans-4-hydroxy-L-proline betaine = cis-4-hydroxy-D-proline betaine |
| RULE(radius=1) | |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine. | Kumar R, Zhao S, Vetting MW, Wood BM, Sakai A, Cho K, Solbiati J, Almo SC, Sweedler JV, Jacobson MP, Gerlt JA, Cronan JE | 2014 Feb 11 | 24520058 |
| Discovery of new enzymes and metabolic pathways by using structure and genome context. | Zhao S, Kumar R, Sakai A, Vetting MW, Wood BM, Brown S, Bonanno JB, Hillerich BS, Seidel RD, Babbitt PC, Almo SC, Sweedler JV, Gerlt JA, Cronan JE, Jacobson MP | 2013 Oct 31 | 24056934 |