Enzyme

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EC Tree
     5. Isomerases
        5.1 Racemases and epimerases
            5.1.1 Acting on amino acids and derivatives
ID:5.1.1.22
Description:4-hydroxyproline betaine 2-epimerase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 5.1.1.22
BRENDA Enzyme Link: BRENDA 5.1.1.22
KEGG Enzyme Link: KEGG5.1.1.22
BioCyc Enzyme Link: BioCyc 5.1.1.22
ExPASy Enzyme Link: ExPASy5.1.1.22
EC2PDB Enzyme Link: EC2PDB 5.1.1.22
ExplorEnz Enzyme Link: ExplorEnz 5.1.1.22
PRIAM enzyme-specific profiles Link: PRIAM 5.1.1.22
IntEnz Enzyme Link: IntEnz 5.1.1.22
MEDLINE Enzyme Link: MEDLINE 5.1.1.22
MSA:

5.1.1.22;

Phylogenetic Tree:

5.1.1.22;

Uniprot:
M-CSA:
RHEA:51884 L-proline betaine = D-proline betaine
RULE(radius=1)
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine.Kumar R, Zhao S, Vetting MW, Wood BM, Sakai A, Cho K, Solbiati J, Almo SC, Sweedler JV, Jacobson MP, Gerlt JA, Cronan JE2014 Feb 1124520058
Discovery of new enzymes and metabolic pathways by using structure and genome context.Zhao S, Kumar R, Sakai A, Vetting MW, Wood BM, Brown S, Bonanno JB, Hillerich BS, Seidel RD, Babbitt PC, Almo SC, Sweedler JV, Gerlt JA, Cronan JE, Jacobson MP2013 Oct 3124056934

RHEA:47544 trans-4-hydroxy-L-proline betaine = cis-4-hydroxy-D-proline betaine
RULE(radius=1)
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine.Kumar R, Zhao S, Vetting MW, Wood BM, Sakai A, Cho K, Solbiati J, Almo SC, Sweedler JV, Jacobson MP, Gerlt JA, Cronan JE2014 Feb 1124520058
Discovery of new enzymes and metabolic pathways by using structure and genome context.Zhao S, Kumar R, Sakai A, Vetting MW, Wood BM, Brown S, Bonanno JB, Hillerich BS, Seidel RD, Babbitt PC, Almo SC, Sweedler JV, Gerlt JA, Cronan JE, Jacobson MP2013 Oct 3124056934