EC number:5.1.1.8
Enzyme
Download| EC Tree |
| 5. Isomerases |
| 5.1 Racemases and epimerases |
| 5.1.1 Acting on amino acids and derivatives |
| ID: | 5.1.1.8 |
|---|---|
| Description: | 4-hydroxyproline epimerase. |
| Alternative Name: |
Hydroxyproline epimerase. Hydroxyproline 2-epimerase. |
| Cath: | 3.10.310.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 5.1.1.8 |
| BRENDA Enzyme Link: | BRENDA 5.1.1.8 |
| KEGG Enzyme Link: | KEGG5.1.1.8 |
| BioCyc Enzyme Link: | BioCyc 5.1.1.8 |
| ExPASy Enzyme Link: | ExPASy5.1.1.8 |
| EC2PDB Enzyme Link: | EC2PDB 5.1.1.8 |
| ExplorEnz Enzyme Link: | ExplorEnz 5.1.1.8 |
| PRIAM enzyme-specific profiles Link: | PRIAM 5.1.1.8 |
| IntEnz Enzyme Link: | IntEnz 5.1.1.8 |
| MEDLINE Enzyme Link: | MEDLINE 5.1.1.8 |
| RHEA:21152 | trans-4-hydroxy-L-proline = cis-4-hydroxy-D-proline |
| RULE(radius=1) | |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks. | Zhao S, Sakai A, Zhang X, Vetting MW, Kumar R, Hillerich B, San Francisco B, Solbiati J, Steves A, Brown S, Akiva E, Barber A, Seidel RD, Babbitt PC, Almo SC, Gerlt JA, Jacobson MP | 2014 Jun 30 | 24980702 |
| Molecular and structural discrimination of proline racemase and hydroxyproline-2-epimerase from nosocomial and bacterial pathogens. | Goytia M, Chamond N, Cosson A, Coatnoan N, Hermant D, Berneman A, Minoprio P | 2007 Sep 12 | 17849014 |
| Kinetic and structural studies of hydroxyproline 2-epimerase. | Finlay TH, Adams E | 1970 Oct 25 | 5469165 |
| Determination of 4-hydroxyproline-2-epimerase activity by capillary electrophoresis: A stereoselective platform for inhibitor screening of amino acid isomerases. | Gavina JM, White CE, Finan TM, Britz-McKibbin P | 2010 Aug | 20665524 |